FGF4 Antikörper (C-Term)

Produktnummer ABIN499836

Der Kaninchen Polyklonal anti-FGF4 Antikörper (ABIN499836) detektiert spezifisch FGF4 in WB, EIA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für FGF4 Antikörper (C-Term) (ABIN499836)

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Produktdetails anti-FGF4 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to FGF4.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: FGF4 antibody was raised against a 18 amino acid peptide near the carboxy terminus of the human FGF4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 0.5 - 1 μg/mLImmunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu FGF4

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Andere Bezeichnung: FGF4

Hintergrund: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.Synonyms: Fibroblast growth factor 4, HST, HST-1, HSTF1, Heparin secretory-transforming protein, Heparin-binding growth factor 4, KS3, Transforming protein KS3

Gen-ID: 2249

UniProt: P08620

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance