FGF4 Antikörper (AA 62-123)

Produktnummer ABIN1724834

Produktdetails anti-FGF4 Antikörper

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Bindungsspezifität: AA 62-123

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of humanFGF4 (AA: 62-123) expressed in E. coli.

Klon: 3A12G9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Referenzen für anti-FGF4 Antikörper (ABIN1724834)

Johannesson, Ståhlberg, Ameri, Sand, Norrman, Semb: "FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner." in: PLoS ONE, Vol. 4, Issue 3, pp. e4794, (2009) (PubMed).

Mayshar, Rom, Chumakov, Kronman, Yayon, Benvenisty: "Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 3, pp. 767-74, (2008) (PubMed).

Details zu FGF4

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Andere Bezeichnung: FGF4 (FGF4 Produkte)

Synonyme: HBGF-4 antikoerper, HST antikoerper, HST-1 antikoerper, HSTF1 antikoerper, K-FGF antikoerper, KFGF antikoerper, Fgf-4 antikoerper, Fgfk antikoerper, Hst1 antikoerper, Hstf-1 antikoerper, KS3 antikoerper, hst antikoerper, hst-1 antikoerper, kFGF antikoerper, Hst antikoerper, fibroblast growth factor 4 antikoerper, FGF4 antikoerper, Fgf4 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Aliases: HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-5

Molekulargewicht: 22 kDa

Gen-ID: 2249

HGNC: 2249

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance