XRCC4 Antikörper (AA 216-269)

Produktnummer ABIN1886206

Produktdetails anti-XRCC4 Antikörper

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Bindungsspezifität: AA 216-269

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 216 and 269 (Q13426) of XRCC4

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu XRCC4

Target: XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))

Andere Bezeichnung: XRCC4 (XRCC4 Produkte)

Synonyme: zgc:73312 antikoerper, MGC81443 antikoerper, homolog of human DNA ligase iv-binding protein XRCC4 antikoerper, 2310057B22Rik antikoerper, AW413319 antikoerper, AW545101 antikoerper, X-ray repair cross complementing 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog antikoerper, DNA ligase IV-binding protein antikoerper, XRCC4 antikoerper, xrcc4 antikoerper, xrcc4.L antikoerper, Xrcc4 antikoerper

Hintergrund: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.The non-homologous end-joining pathway is required both for normal development and for suppression of tumors.This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes.Alternative transcription initiation and alternative splicing generates several transcript variants.[provided by RefSeq]

Molekulargewicht: 38 kDa

Gen-ID: 7518

NCBI Accession: NP_071801, NM_022406

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response