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XRCC4 Antikörper

XRCC4 Reaktivität: Human WB, IF, IP, IHC (p) Wirt: Maus Monoclonal 8K2 unconjugated
Produktnummer ABIN7250143
  • Target Alle XRCC4 Antikörper anzeigen
    XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
    Reaktivität
    • 68
    • 26
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 63
    • 5
    Maus
    Klonalität
    • 65
    • 3
    Monoklonal
    Konjugat
    • 30
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XRCC4 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 23
    • 13
    • 13
    • 10
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Produktmerkmale
    Monoclonal Antibody
    Aufreinigung
    Protein A purification
    Immunogen
    Synthetic Peptide
    Klon
    8K2
    Isotyp
    IgG
    Top Product
    Discover our top product XRCC4 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
    Andere Bezeichnung
    XRCC4 (XRCC4 Produkte)
    Synonyme
    zgc:73312 antikoerper, MGC81443 antikoerper, homolog of human DNA ligase iv-binding protein XRCC4 antikoerper, 2310057B22Rik antikoerper, AW413319 antikoerper, AW545101 antikoerper, X-ray repair cross complementing 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog antikoerper, DNA ligase IV-binding protein antikoerper, XRCC4 antikoerper, xrcc4 antikoerper, xrcc4.L antikoerper, Xrcc4 antikoerper
    Hintergrund
    Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
    Molekulargewicht

    Observed_MW: 38 kDa

    Calculated_MW: 38 kDa

    UniProt
    Q13426
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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