DcR1 Antikörper (FITC)

Produktnummer ABIN181101

Produktdetails anti-DcR1 Antikörper (FITC)

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DcR1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: This antibody recognises CD263, a 60 kDa cell surface protein.

Produktmerkmale: Synonyms: Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3, Tumor necrosisfactor receptor superfamily member 10C, Decoy TRAIL receptor without death domain,TNF-related apoptosis-inducing ligand receptor 3, Trail receptor without an intracellulardomain, Lymphocyte inhibitor of TRAIL, Antagonist decoy receptor for TRAIL/Apo-2L

Aufreinigung: Affinity chromatography on Protein G

Immunogen: DcR1-Fc chimaeric protein. Lymph node cells from immunised mice were fused with cells ofthe P3U1 myeloma cell line.

Klon: 2B8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry (Neat - 1/10): use 10 μL of the suggested working dilution to label 1x10^6cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu DcR1

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Andere Bezeichnung: CD263 / TRAILR3 (TNFRSF10C Produkte)

Synonyme: CD263 antikoerper, DCR1 antikoerper, DCR1-TNFR antikoerper, LIT antikoerper, TRAIL-R3 antikoerper, TRAILR3 antikoerper, TRID antikoerper, TNFRSF10C antikoerper, TNF receptor superfamily member 10c antikoerper, TNFRSF10C antikoerper

Hintergrund: CD263 is a member of the tumour necrosis factor (TNF) receptor superfamily that binds to TNF-related apoptosis inducing ligand (TRAIL). As the receptor does not possess cytoplasmic death domains it cannot induce apoptosis, but instead plays an important role in inhibiting TRAIL-induced apoptosis. CD263 is expressed in normal tissues including heart, skeletal tissues and peripheral blood neutrophils, but weakly expressed in tumour cells.Synonyms: Antagonist decoy receptor for TRAIL/Apo-2L, DCR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRID, Trail receptor without an intracellular domain, Tumor necrosis factor receptor superfamily member 10C

Gen-ID: 8794

UniProt: O14798

Pathways: Apoptose