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PINK1 Antikörper (AA 258-274)

PINK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1738105
  • Target Alle PINK1 Antikörper anzeigen
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Bindungsspezifität
    • 20
    • 12
    • 11
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-274
    Reaktivität
    • 89
    • 48
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 70
    • 32
    • 1
    Kaninchen
    Klonalität
    • 74
    • 31
    Polyklonal
    Konjugat
    • 48
    • 10
    • 9
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PINK1 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 52
    • 47
    • 17
    • 15
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Reacts with human PINK1
    Aufreinigung
    Antigen affinity purified
    Immunogen
    Synthetic peptide made residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1.
    Isotyp
    IgG
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  • Applikationshinweise

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    WB1:100-1:2000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, Sodium azide 0.02 %
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Haltbarkeit
    6 months
  • Target
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Andere Bezeichnung
    PINK1 (PINK1 Produkte)
    Synonyme
    BEST:GH23468 antikoerper, CG4523 antikoerper, Dmel\\CG4523 antikoerper, PINK antikoerper, PINK1 antikoerper, dPINK1 antikoerper, dPink1 antikoerper, pink1 antikoerper, wu:fc39e12 antikoerper, zgc:101729 antikoerper, BRPK antikoerper, PARK6 antikoerper, 1190006F07Rik antikoerper, AU042772 antikoerper, AW557854 antikoerper, mFLJ00387 antikoerper, PTEN-induced putative kinase 1 antikoerper, PTEN induced putative kinase 1 antikoerper, Pink1 antikoerper, PINK1 antikoerper, pink1 antikoerper
    Hintergrund
    PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.
    Gen-ID
    65018
    Pathways
    Autophagie
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