PINK1 Antikörper (AA 258-274)
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- Target Alle PINK1 Antikörper anzeigen
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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Bindungsspezifität
- AA 258-274
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PINK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- Reacts with human PINK1
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Synthetic peptide made residues 258-274 (YRKSKRGPKQLAPHPNI) of human PINK1.
- Isotyp
- IgG
- Top Product
- Discover our top product PINK1 Primärantikörper
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- Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB1:100-1:2000 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, Sodium azide 0.02 %
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Haltbarkeit
- 6 months
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- Target
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- Andere Bezeichnung
- PINK1 (PINK1 Produkte)
- Synonyme
- BEST:GH23468 antikoerper, CG4523 antikoerper, Dmel\\CG4523 antikoerper, PINK antikoerper, PINK1 antikoerper, dPINK1 antikoerper, dPink1 antikoerper, pink1 antikoerper, wu:fc39e12 antikoerper, zgc:101729 antikoerper, BRPK antikoerper, PARK6 antikoerper, 1190006F07Rik antikoerper, AU042772 antikoerper, AW557854 antikoerper, mFLJ00387 antikoerper, PTEN-induced putative kinase 1 antikoerper, PTEN induced putative kinase 1 antikoerper, Pink1 antikoerper, PINK1 antikoerper, pink1 antikoerper
- Hintergrund
- PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.
- Gen-ID
- 65018
- Pathways
- Autophagie
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