PINK1 Antikörper (AA 282-581)

Produktnummer ABIN6145665

Produktdetails anti-PINK1 Antikörper

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Bindungsspezifität: AA 282-581

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PINK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: TSSVPLLPGA LVDYPDVLPS RLHPEGLGHG RTLFLVMKNY PCTLRQYLCV NTPSPRLAAM MLLQLLEGVD HLVQQGIAHR DLKSDNILVE LDPDGCPWLV IADFGCCLAD ESIGLQLPFS SWYVDRGGNG CLMAPEVSTA RPGPRAVIDY SKADAWAVGA IAYEIFGLVN PFYGQGKAHL ESRSYQEAQL PALPESVPPD VRQLVRALLQ REASKRPSAR VAANVLHLSL WGEHILALKN LKLDKMVGWL LQQSAATLLA NRLTEKCCVE TKMKMLFLAN LECETLCQAA LLLCSWRAAL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-PINK1 Antikörper (ABIN6145665)

Ren, Li, Yan, Ma, Zhou, Xue, Zhang, Liu, Yang, Jia, Zhang, Zhang, Mu, Zhang, Da: "Adiponectin modulates oxidative stress-induced mitophagy and protects C2C12 myoblasts against apoptosis." in: Scientific reports, Vol. 7, Issue 1, pp. 3209, (2018) (PubMed).

Details zu PINK1

Target: PINK1 (PTEN Induced Putative Kinase 1 (PINK1))

Andere Bezeichnung: PINK1 (PINK1 Produkte)

Synonyme: BEST:GH23468 antikoerper, CG4523 antikoerper, Dmel\\CG4523 antikoerper, PINK antikoerper, PINK1 antikoerper, dPINK1 antikoerper, dPink1 antikoerper, pink1 antikoerper, wu:fc39e12 antikoerper, zgc:101729 antikoerper, BRPK antikoerper, PARK6 antikoerper, 1190006F07Rik antikoerper, AU042772 antikoerper, AW557854 antikoerper, mFLJ00387 antikoerper, PTEN-induced putative kinase 1 antikoerper, PTEN induced putative kinase 1 antikoerper, Pink1 antikoerper, PINK1 antikoerper, pink1 antikoerper

Hintergrund: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.,PINK1,BRPK,PARK6,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Cardiovascular,Heart,Cardiac metabolism,Mitochondrial Control of Autophagy,PINK1

Molekulargewicht: 30 kDa/62 kDa

Gen-ID: 65018

UniProt: Q9BXM7

Pathways: Autophagie