BCL3 Antikörper (FITC)

Produktnummer ABIN161382

Produktdetails anti-BCL3 Antikörper (FITC)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser BCL3 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Spezifität: Mouse Bcl-3

Aufreinigung: Purified from ascites via Protein G Chromatography

Immunogen: recombinant Bcl-3-6-histidine tag . Fusion Partner: SP2/0 myeloma . Donor: Armenian Hamster

Klon: Ham 150-3-5

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: Bcl-3 (BCL3 Produkte)

Synonyme: BCL3 antikoerper, AI528691 antikoerper, Bcl-3 antikoerper, BCL4 antikoerper, D19S37 antikoerper, B-cell CLL/lymphoma 3 antikoerper, B cell leukemia/lymphoma 3 antikoerper, BCL3 antikoerper, Bcl3 antikoerper

Hintergrund: Anti-mouse Bcl-3 monoclonal antibody reacts with both mouse and human Bcl-3 (B-cell Leukemia/lymphoma 3). The proto-oncoprotein Bcl-3 is a member of the IkappaB family and is present predominantly in the nucleus. This protein has been shown to function as a transcriptional co-activator for homodimers of NF-kappaB p50 and p50B. In addition to p50 and p52, Bcl-3 also associates with nuclear proteins Jab1, Pirin, Tip60 and Bard1. The mouse Bcl-3 coding region exhibits 80% homology with human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs. Applications for this clone include Western blotting, ELISA and flow cytometry.

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus