BCL3 Antikörper (Center)

Produktnummer ABIN653286

Produktdetails anti-BCL3 Antikörper

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Bindungsspezifität: AA 249-277, Center

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.

Klon: RB23954

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.48 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-BCL3 Antikörper (ABIN653286)

Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." in: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: BCL3 (BCL3 Produkte)

Synonyme: BCL3 antikoerper, AI528691 antikoerper, Bcl-3 antikoerper, BCL4 antikoerper, D19S37 antikoerper, B-cell CLL/lymphoma 3 antikoerper, B cell leukemia/lymphoma 3 antikoerper, BCL3 antikoerper, Bcl3 antikoerper

Hintergrund: BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3

Molekulargewicht: 46800 Da

Gen-ID: 602

UniProt: P20749

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus