BCL3 Antikörper (AA 300-400)

Produktnummer ABIN6137509

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BCL3 in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für BCL3 Antikörper (AA 300-400) (ABIN6137509)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-BCL3 Antikörper

Bindungsspezifität: AA 300-400

Sequenz: ANVNAQMYSG SSALHSASGR GLLPLVRTLV RSGADSSLKN CHNDTPLMVA RSRRVIDILR GKATRPASTS QPDPSPDRSA NTSPESSSRL SSNGLLSASP S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human BCL3 (NP_005169.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: BCL3

Hintergrund: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.,BCL3,BCL4,D19S37,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,NF-kB Signaling Pathway,BCL3

Molekulargewicht: 47 kDa

Gen-ID: 602

UniProt: P20749

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus