Androgen Receptor Antikörper
-
- Target Alle Androgen Receptor (AR) Antikörper anzeigen
- Androgen Receptor (AR)
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Androgen Receptor Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- Purified His-tagged Androgen Receptor Protein(Fragment) was used to produced this monoclonal antibody.
- Klon
- 549CT16-1-4
- Isotyp
- IgA
- Top Product
- Discover our top product AR Primärantikörper
-
-
- Applikationshinweise
- WB: 1:100~250
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Androgen Receptor Protein can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Haltbarkeit
- 6 months
-
- Target
- Androgen Receptor (AR)
- Andere Bezeichnung
- Androgen Receptor (AR Produkte)
- Synonyme
- AIS antikoerper, DHTR antikoerper, HUMARA antikoerper, HYSP1 antikoerper, KD antikoerper, NR3C4 antikoerper, SBMA antikoerper, SMAX1 antikoerper, TFM antikoerper, AW320017 antikoerper, Tfm antikoerper, Andr antikoerper, AR antikoerper, androgen receptor antikoerper, AR antikoerper, Ar antikoerper, ar antikoerper
- Hintergrund
- The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].
- Molekulargewicht
- 99188
- Gen-ID
- 367
- NCBI Accession
- NP_000035, NP_001011645
- UniProt
- P10275
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
-