ATP2A2 Antikörper (AA 374-403)

Produktnummer ABIN1538370

Produktdetails anti-ATP2A2 Antikörper

Target: ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))

Bindungsspezifität: AA 374-403

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP2A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2.

Klon: RB36768

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ATP2A2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu ATP2A2

Target: ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))

Andere Bezeichnung: ATP2A2 (ATP2A2 Produkte)

Synonyme: atp2b antikoerper, ca-p60a antikoerper, dar antikoerper, serca2 antikoerper, ATP2A2 antikoerper, ATP2B antikoerper, DAR antikoerper, DD antikoerper, SERCA2 antikoerper, SERCA2A antikoerper, ATP2 antikoerper, Serca2 antikoerper, SercaII antikoerper, 9530097L16Rik antikoerper, D5Wsu150e antikoerper, SERCA2B antikoerper, mKIAA4195 antikoerper, atp2a2 antikoerper, zgc:55380 antikoerper, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog antikoerper, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a antikoerper, atp2a1.S antikoerper, ATP2A2 antikoerper, Atp2a2 antikoerper, atp2a2a antikoerper

Hintergrund: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 114757

Gen-ID: 488

NCBI Accession: NP_001672, NP_733765

UniProt: P16615

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process