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ATP2A2 Antikörper (AA 111-253)

ATP2A2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021430
  • Target Alle ATP2A2 Antikörper anzeigen
    ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-253
    Reaktivität
    • 55
    • 29
    • 29
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 1
    • 1
    Kaninchen
    Klonalität
    • 45
    • 11
    Polyklonal
    Konjugat
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ATP2A2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 23
    • 13
    • 7
    • 7
    • 5
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    NAENAIEALK EYEPEMGKVY RQDRKSVQRI KAKDIVPGDI VEIAVGDKVP ADIRLTSIKS TTLRVDQSIL TGESVSVIKH TDPVPDPRAV NQDKKNMLFS GTNIAAGKAM GVVVATGVNT EIGKIRDEMV ATEQERTPLQ QKL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 111-253 of human SERCA2/ATP2A2 (NP_733765.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ATP2A2 (ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2))
    Andere Bezeichnung
    ATP2A2 (ATP2A2 Produkte)
    Synonyme
    atp2b antikoerper, ca-p60a antikoerper, dar antikoerper, serca2 antikoerper, ATP2A2 antikoerper, ATP2B antikoerper, DAR antikoerper, DD antikoerper, SERCA2 antikoerper, SERCA2A antikoerper, ATP2 antikoerper, Serca2 antikoerper, SercaII antikoerper, 9530097L16Rik antikoerper, D5Wsu150e antikoerper, SERCA2B antikoerper, mKIAA4195 antikoerper, atp2a2 antikoerper, zgc:55380 antikoerper, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 S homeolog antikoerper, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 antikoerper, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a antikoerper, atp2a1.S antikoerper, ATP2A2 antikoerper, Atp2a2 antikoerper, atp2a2a antikoerper
    Hintergrund
    This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.,ATP2B,DAR,DD,SERCA2,ATP2A2/SERCA2,ATP2A2,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,Cardiovascular,Heart,Contractility,ATP2A2
    Molekulargewicht
    109 kDa/111 kDa/114 kDa
    Gen-ID
    488
    UniProt
    P16615
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process
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