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DcR1 Antikörper

TNFRSF10C Reaktivität: Human Func Wirt: Maus Monoclonal B-D44 unconjugated
Produktnummer ABIN1106169
  • Target Alle DcR1 (TNFRSF10C) Antikörper anzeigen
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Reaktivität
    • 60
    • 8
    • 7
    • 6
    Human
    Wirt
    • 41
    • 24
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 43
    • 25
    Monoklonal
    Konjugat
    • 33
    • 8
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DcR1 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 24
    • 24
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Functional Studies (Func)
    Spezifität
    Recognizes the soluble antigen. Recognizes the 75-90 kDa protein.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Ion Exchange Chromatography.
    Sterilität
    0.22 μm filtered
    Immunogen
    Recombinant Human TRAIL R3/Fc chimera. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
    Klon
    B-D44
    Isotyp
    IgG1
    Top Product
    Discover our top product TNFRSF10C Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Andere Bezeichnung
    CD263 / TRAILR3 (TNFRSF10C Produkte)
    Synonyme
    CD263 antikoerper, DCR1 antikoerper, DCR1-TNFR antikoerper, LIT antikoerper, TRAIL-R3 antikoerper, TRAILR3 antikoerper, TRID antikoerper, TNFRSF10C antikoerper, TNF receptor superfamily member 10c antikoerper, TNFRSF10C antikoerper
    Hintergrund
    TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).Synonyms: Antagonist decoy receptor for TRAIL/Apo-2L, DCR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRID, Trail receptor without an intracellular domain, Tumor necrosis factor receptor superfamily member 10C
    Gen-ID
    8794
    NCBI Accession
    NP_003832
    UniProt
    O14798
    Pathways
    Apoptose
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