Angiotensin II Antikörper

Produktnummer ABIN1077791

Produktdetails anti-Angiotensin II Antikörper

Target: Angiotensin II (Ang II)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Polyclonal Antibody to Angiotensin II (AngII)

Spezifität: The antibody is a rabbit polyclonal antibody raised against AngII. It has been selected for its ability to recognize AngII in immunohistochemical staining and western blotting.

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: OVA Conjugated Angiotensin II (AngII)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze/thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Referenzen für anti-Angiotensin II Antikörper (ABIN1077791)

Kehoe, Al Mulhim, Zetterberg, Blennow, Miners: "Cerebrospinal Fluid Changes in the Renin-Angiotensin System in Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 72, Issue 2, pp. 525-535, (2020) (PubMed).

Details zu Angiotensin II

Target: Angiotensin II (Ang II)

Andere Bezeichnung: Angiotensin II (Ang II Produkte)

Synonyme: ANHU antikoerper, SERPINA8 antikoerper, ANRT antikoerper, Ang antikoerper, AngII antikoerper, PAT antikoerper, AI265500 antikoerper, AngI antikoerper, Aogen antikoerper, Serpina8 antikoerper, angiotensinogen antikoerper, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antikoerper, AGT antikoerper, Agt antikoerper

Hintergrund: Ang-II, Angiotensin-2

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity