BCL3 Antikörper (C-Term)

Produktnummer ABIN1077425

Produktdetails anti-BCL3 Antikörper

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal BCL3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human BCL3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: BCL3 antibody can be used for detection of BCL3 by Western blot at 1 - 2 μg/mL.

Kommentare:

(CT) B-cell CLL/lymphoma 3

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: BCL3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: BCL3 (BCL3 Produkte)

Synonyme: BCL3 antikoerper, AI528691 antikoerper, Bcl-3 antikoerper, BCL4 antikoerper, D19S37 antikoerper, B-cell CLL/lymphoma 3 antikoerper, B cell leukemia/lymphoma 3 antikoerper, BCL3 antikoerper, Bcl3 antikoerper

Hintergrund: The proto-oncogene Bcl-3, believed to be involved in certain human B cell leukemias, encodes a protein that contributes to the regulation of transcriptional activation of NF-k-B target genes. BCL3 contains seven ankyrin repeats, which are most closely related to those found in I-k-B proteins. The expression of this gene can be induced by NF-k-B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-k-B. It contributes to the regulation of cell proliferation. A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia.
Synonyms: B-cell CLL/lymphoma 3, BCL-3, BCL4, D19S37, Proto-oncogene BCL3

Molekulargewicht: 50 kDa (calculated)

Gen-ID: 602

NCBI Accession: NP_005169

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus