Serine/Threonine Kinase 10 Proteine (STK10)

STK10 encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. Zusätzlich bieten wir Ihnen Serine/Threonine Kinase 10 Antikörper (92) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
STK10 6793 O94804
STK10 20868 O55098
Ratte STK10 STK10 29398  
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Top Serine/Threonine Kinase 10 Proteine auf antikoerper-online.de

Showing 8 out of 9 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$338.80
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$352.75
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
$310.00
Details
Insektenzellen Human Unkonjugiert 5 μg Anmelden zum Anzeigen 11 bis 12 Tage
$613.33
Details

STK10 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine)

Weitere Proteine zu Serine/Threonine Kinase 10 (STK10) Interaktionspartnern

Human Serine/Threonine Kinase 10 (STK10) Interaktionspartner

  1. Binding of phosphatidylinositol 4,5-biphosphate to ezrin (zeige EZR Proteine) induces a conformational change permitting the insertion of the LOK C-terminal domain to wedge apart the membrane and F-actin-binding domains of ezrin (zeige EZR Proteine). The N-terminal LOK kinase domain can then access a site 40 residues distal from the consensus sequence that collectively direct phosphorylation of the appropriate threonine residue.

  2. The gene signature of OPA1 (zeige OPA1 Proteine), CTSA (zeige CTSA Proteine), NDUFA1 (zeige NDUFA1 Proteine), STK10 and PRDX1 (zeige PRDX1 Proteine) was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls.

  3. STK10 functions as a tumor suppressor gene, and dysfunction of STK10 activity either through polymorphism or somatic mutations may confer anti-apoptotic effects contributing to carcinogenesis.

  4. It was shown that lymphocyte-oriented and STE20 kinase (zeige SLK Proteine) were sufficient to restrict ezrin (zeige EZR Proteine) function to the apical domain. Both kinases were enriched in microvilli and locally activated there.

  5. Opposing roles of serine/threonine kinases MEKK1 (zeige MAP3K1 Proteine) and LOK in regulating the CD28 (zeige CD28 Proteine) responsive element in T-cells

  6. Stk10 is a novel polo-like kinase kinase that cooperates with hSlk to regulate Plk1 function in human cells

  7. These studies identify a new ERM (zeige ETV5 Proteine) kinase of importance in lymphocytes and confirm the role of ezrin-radixin-moesin (zeige MSN Proteine) phosphorylation in regulating cell shape and motility.

Mouse (Murine) Serine/Threonine Kinase 10 (STK10) Interaktionspartner

  1. kinases, including Slk (zeige SLK Proteine), Lok and Mst1 (zeige MST1 Proteine), are inhibited by BI-D1870 but to a much lesser extent by BIX 02565 and that phosphorylation of some of their substrates is blocked by BI-D1870 in living cells.

  2. Stk10 is a novel polo-like kinase kinase that cooperates with hSlk to regulate Plk1 function in human cells

  3. These studies identify a new ERM (zeige ETV5 Proteine) kinase of importance in lymphocytes and confirm the role of ezrin-radixin-moesin (zeige MSN Proteine) phosphorylation in regulating cell shape and motility.

Serine/Threonine Kinase 10 (STK10) Protein Überblick

Protein Überblick

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.

Genbezeichner und Symbole assoziert mit STK10

  • serine/threonine kinase 10 (STK10)
  • serine/threonine kinase 10 S homeolog (stk10.S)
  • serine/threonine kinase 10 (Stk10)
  • serine/threonine kinase 10 (stk10)
  • Gek1 Protein
  • Lok Protein
  • mKIAA4026 Protein
  • plkk1 Protein
  • PRO2729 Protein
  • stk10 Protein
  • xPlkk1 Protein
  • zgc:63495 Protein

Bezeichner auf Proteinebene für STK10

lymphocyte-oriented kinase , serine/threonine-protein kinase 10 , polo-like kinase kinase 1 , serine/threonine-protein kinase 10-A , germ cell kinase 1

GENE ID SPEZIES
6793 Homo sapiens
373731 Xenopus laevis
20868 Mus musculus
416204 Gallus gallus
526376 Bos taurus
29398 Rattus norvegicus
394108 Danio rerio
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