anti-Regucalcin (RGN) Antikörper

The protein encoded by RGN is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. Zusätzlich bieten wir Ihnen Regucalcin Kits (19) und Regucalcin Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RGN 19733 Q64374
RGN 9104 Q15493
RGN 25106 Q03336
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Top anti-Regucalcin Antikörper auf

Showing 10 out of 44 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-Regucalcin/SMP30 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB stainin 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Maus Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage

RGN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Regucalcin Interaktionspartner

Zebrafish Regucalcin (RGN) Interaktionspartner

  1. SMP30/RGN is important for liver proliferation and tumorigenesis.

Mouse (Murine) Regucalcin (RGN) Interaktionspartner

  1. The phosphorylated eNOS (zeige NOS3 Antikörper) and Akt (zeige AKT1 Antikörper) levels and VEGF (zeige VEGFA Antikörper) levels in ischemic muscle were lower in SMP30 KO and old mice than in young mice. Deficiency of SMP30 exacerbates oxidative stress related to NADPH oxidase (zeige NOX1 Antikörper) activity enhancement and impairs eNOS (zeige NOS3 Antikörper) activity, which leads to rarefaction of angiogenesis induced by ischemia

  2. Results suggested that SMP30 deficiency augments myocardial Ischemia/Reperfusion injury through reactive oxygen species generation and attenuation of Akt (zeige AKT1 Antikörper) activation.

  3. This is the first report that stem cell replacement increased the expression of SMP30 in the liver, and may help prevent fibrosis in the liver of db/db (zeige LEPR Antikörper) mice.

  4. SMP30/GNL-positive cells localized around the central veins of livers of mice and decreased numerically with aging. Nuclear SMP30/GNL protein might be a regulatory factor specific for genes whose expression governs transcription and the aging process.

  5. SMP30 may be a potent inhibitory protein against oxidative stress and chronic inflammation.

  6. SMP30 plays an important role in the regulation of coronary vascular tone by myocardium.

  7. These results suggested that SMP30 might be involved in overriding the apoptotic homeostatic mechanism in response to DNA damage.

  8. SMP30 deficiency is closely associated with non-alcoholic fatty liver disease pathogenesis.

  9. left ventricular ejection fraction was more severely reduced in the DOX-treated SMP30 KO mice than in the DOX-treated WT mice, but was preserved in the DOX-treated SMP30 TG mice

  10. Results from using this unique model of AA deficiency, the SMP30/GNL-KO mouse, now provide new information about formerly unknown AA functions that will implement further study of AA in vivo.

Human Regucalcin (RGN) Interaktionspartner

  1. These findings suggest that regucalcin may play a potential role as a suppressor of human lung cancer, and that downregulation of regucalcin expression may predispose patients to development of lung cancer.

  2. The role of RGN suppressing cell proliferation is associated with the regulation of expression of oncogenes and tumor suppressor genes. [review]

  3. High RGN expression is associated with hepatocellular carcinoma.

  4. the present study suggests that regucalcin may have important anticancer properties in human breast cancer patients. Mechanistically, these effects are likely mediated through suppression of multiple signaling pathways, upregulation of p53 (zeige TP53 Antikörper) and downregulation of oncogenes leading to anti-proliferative effects and reduced metastases to bone, a phenotype associated with poor clinical outcome.

  5. Study demonstrates that increased regucalcin gene expression greatly contributes to prolonged survival in human pancreatic cancer patients. Morover, overexpression of regucalcin was found to suppress the proliferation, which is enhanced through various signaling pathways.

  6. Study results suggest that senescence marker protein-30 and senescence-associated beta-galactosidase (zeige GLB1 Antikörper) expressions in both nuclear cataract and cortical cataract patients were associated with lens epithelial cells apoptosis.

  7. data suggest that exogenous regucalcin exerts suppressive effects on the proliferation of human pancreatic cancer cells.

  8. immunohistochemistry revealed a significant decrease of regucalcin in human kidney disease tissue vs control kidney tissue, and regucalcin was detected in exosomes isolated from healthy donors' urine but not from kidney disease patients

  9. results highlighted the importance of RGN as a regulatory protein in Ca2 (zeige CA2 Antikörper)+-dependent signaling pathways and its deregulation of RGN expression by Ca2 (zeige CA2 Antikörper)+o may contribute for onset and progression of PCa (zeige FLVCR1 Antikörper).

  10. This review will discuss regarding to an involvement of regucalcin as a suppressor protein in human carcinogenesis in insight into the gene therapy. [review]

Cow (Bovine) Regucalcin (RGN) Interaktionspartner

  1. estrogen administration down-regulated RGN gene expression in the accessory sex glands of veal calves and beef cattle, while androgen treatment reduced RGN gene expression only in the testis.

Regucalcin (RGN) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein.

Genbezeichner und Symbole assoziert mit anti-Regucalcin (RGN) Antikörper

  • CG1803 gene product from transcript CG1803-RA (regucalcin) Antikörper
  • regucalcin (rgn) Antikörper
  • regucalcin (LOC465598) Antikörper
  • regucalcin (RGN) Antikörper
  • GE16489 gene product from transcript GE16489-RB (Dyak\regucalcin) Antikörper
  • regucalcin (senescence marker protein-30) (RGN) Antikörper
  • regucalcin (Rgn) Antikörper
  • regucalcin L homeolog (rgn.L) Antikörper
  • AI265316 Antikörper
  • CG1803 Antikörper
  • Dmel\\CG1803 Antikörper
  • DyakGE16489 Antikörper
  • dyak_GLEANR_17905 Antikörper
  • GE16489 Antikörper
  • GNL Antikörper
  • Rc Antikörper
  • Reguc Antikörper
  • regucalcin Antikörper
  • rgn-A Antikörper
  • SMP-30 Antikörper
  • SMP30 Antikörper
  • T1 Antikörper
  • xsmp-30 Antikörper
  • xsmp30 Antikörper
  • zgc:92078 Antikörper

Bezeichner auf Proteinebene für anti-Regucalcin (RGN) Antikörper

CG1803-PA , CG1803-PB , CG1803-PC , CG1803-PD , regucalcin-PA , regucalcin-PB , regucalcin-PC , regucalcin-PD , RC , gluconolactonase , regucalcin , regucalcin (senescence marker protein-30) , DyakGE16489-PA , Dyakregucalcin-PA , GE16489-PA , SMP-30 , senescence marker protein 30 , senescence marker protein-30 , xSMP-30

32165 Drosophila melanogaster
403070 Danio rerio
448549 Xenopus (Silurana) tropicalis
465598 Pan troglodytes
480893 Canis lupus familiaris
6523987 Drosophila yakuba
100060684 Equus caballus
100171395 Ovis aries
100174578 Pongo abelii
100196365 Salmo salar
100528098 Ictalurus punctatus
19733 Mus musculus
9104 Homo sapiens
395480 Gallus gallus
373659 Xenopus laevis
25106 Rattus norvegicus
768107 Sus scrofa
280910 Bos taurus
100008619 Oryctolagus cuniculus
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