anti-Paired Box 5 (PAX5) Antikörper

PAX5 encodes a member of the paired box (PAX) family of transcription factors. Zusätzlich bieten wir Ihnen PAX5 Proteine (7) und PAX5 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAX5 5079 Q02548
PAX5 500453  
PAX5 18507 Q02650
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Top anti-PAX5 Antikörper auf antikoerper-online.de

Showing 10 out of 228 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-PAX5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184804 staining (3µg/ml) of U937 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
Details
Human Maus Unkonjugiert ELISA, IHC, WB Western blot analysis of PAX5 over-expressed 293 cell line, cotransfected with PAX5 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of PAX5 expression in transfected 293T cell line by PAX5 monoclonal antibody (M01), clone 8F9. Lane 1: PAX5 transfected lysate(42.1 KDa). Lane 2: Non-transfected lysate. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Kaninchen Unkonjugiert EIA, WB PAX5 Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. PAX5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAX5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using PAX5 mAb against human PAX5 recombinant protein. (Expected MW is 41.2 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$577.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of PAX5 expression in A549 (A), Raji (B), K562 (C), U937 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Tonsil, antibody was diluted at 1:100. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Alexa Fluor 647 FACS Detection of Pax5/BSAP in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$189.84
Details
Human Kaninchen Alexa Fluor 488 FACS Detection of Pax5/BSAP in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 APC-conjugated Monoclonal Antibody. 25 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$189.84
Details

Am meisten referenzierte anti-PAX5 Antikörper

  1. Human Monoclonal PAX5 Primary Antibody für IHC, ELISA - ABIN1098104 : OBrien, Morin, Ouellette, Robichaud: The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease. in Cancer research 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal PAX5 Primary Antibody für ELISA, WB - ABIN969552 : Coyaud, Struski, Prade, Familiades, Eichner, Quelen, Bousquet, Mugneret, Talmant, Pages, Lefebvre, Penther, Lippert, Nadal, Taviaux, Poppe, Luquet, Baranger, Eclache, Radford, Barin, Mozziconacci et al.: Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study. ... in Blood 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PAX5 Interaktionspartner

Human Paired Box 5 (PAX5) Interaktionspartner

  1. The functional role of PAX5-ELN as a potent oncoprotein in B-cell acute lymphoblastic leukemia development.

  2. PAX5 gene methylation can predict poor survival outcomes and cisplatin sensitivity in esophageal squamous cell carcinomaand could be a useful diagnostic tool for cancer therapy selection

  3. Study demonstrated that Pax-5 regulates numerous miRNAs including miR-215 which is aberrantly under-expressed in breast cancer tumors. Pax-5 was found to inhibit aggressive features of breast cancer cells in a miR-215- dependent manner.

  4. The correlation between Pax5 deletion and patients survival in Iranian children with precursor B-cell acute lymphocytic leukemia hs been reported.

  5. this study demonstrates a role for the AHR in regulating human B cell development, and it suggests that transcriptional alterations of PAX5 by the AHR are involved in the underlying mechanism

  6. These findings suggested that pax5 is critically important for the proliferation and survival of pre-B cells.

  7. a mechanism of transcriptional regulation mediated by p27, Pax5, and PCAF

  8. Data show that paired box gene 5 (B-cell lineage specific activator) protein (Pax-5) induces E-cadherin expression in breast cancer cells.

  9. a new function of PAX5 in regulating RIP1 and RIP2 activation, which is at least involved in chemotherapeutic drug resistance in B-lymphoproliferative disorders, is reported.

  10. PAX5-KIDINS220 fusion is associated with Philadelphia-like acute lymphoblastic leukemia.

  11. this study shows that Pax5 expression is lower in antibody-secreting cells than in naive B cells or plasmablasts

  12. The histological observations suggested that the patients represent diverse cases of NHL like mature B-cell type, mature T-cell type and high grade diffuse B-cell type NHL. The findings indicate that patients with NHL may also be analyzed for status of PAX5, CD19 and ZAP70, and their transcriptional and post-translational variants for the differential diagnosis of NHL and therapy.

  13. B cell receptor signaling component, SYK, caused PAX5 tyrosine phosphorylation in vitro and in cells. Transcriptional repression on the BLIMP1 promoter by PAX5 was attenuated by this phosphorylation.

  14. PAX5 haploinsufficiency promotes tumorigenesis and may be related to genomic instability, immune tolerance, and tumor pathways

  15. FISH studies showed false-negative results in 10, 40, and 28% of the samples tested for the IKZF1,PAX5, and CDKN2A/B gene deletions, respectively. The PAX5 and IKZF1 abnormalities are highly specific to B-ALL and can be used as diagnostic markers

  16. The Correlation between GATA5, WT1 and PAX5 methylation and clinical/histological parameters is suggestive of applicability of these markers in non-invasive (epi)genetic testing in hepatocellular carcinoma (HCC).

  17. we identified gene promoter methylation signatures (WT1, MSH6, GATA5 and PAX5) that are strongly correlated to, and can have a predictive value for the clinical outcome of oral squamous cell carcinoma patients

  18. PAX5 expression is infrequent (27.27%) in Olfactory neuroblastoma; however, if present it can be associated with a very aggressive clinical course.

  19. Report Pax5 expression is common in combined Merkel cell carcinoma.

  20. PAX5 was found to be an epigenetically inactivated tumor suppressor that inhibited non-small-cell lung proliferation and metastasis, through down-regulating the beta-catenin pathway and up-regulating GADD45G expression.

Xenopus laevis Paired Box 5 (PAX5) Interaktionspartner

  1. Pax5 transcription factor cooperates in patterning the Xenopus brain.

Mouse (Murine) Paired Box 5 (PAX5) Interaktionspartner

  1. The co-localization of Pax5 and Iba1 was evident in microglia in almost all evaluated regions of brain

  2. identify Pax5 and cyclin D1 as Zfp521 target genes

  3. Together with similar observations made in human PAX5-ETV6(+) B-ALLs, these data identified PAX5-ETV6 fusion as a potent oncoprotein that drives B-cell leukemia development.

  4. PAX5 was found to be an epigenetically inactivated tumor suppressor that inhibited non-small-cell lung proliferation and metastasis, through down-regulating the beta-catenin pathway and up-regulating GADD45G expression.

  5. Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in mantle cell lymphoma independent of CCND1.

  6. Spleen-specific isoform of Pax5 and Ataxin-7 can be considered as spleen-specific unique molecular markers for the evaluation of splenomegaly and lympho-proliferative disorders.

  7. Pax5 and Ebf1 collaborate to modulate the transcriptional response to Notch signaling, and their combined heterozygous loss allows for T-lineage conversion of B cell progenitors.

  8. a dramatic increase in the frequency of pro-B cell leukemia was observed in mice with combined heterozygous mutations in the Ebf1 and Pax5 genes, revealing a synergistic effect of combined dose reduction of these proteins

  9. These results show that in contrast to simple Pax5 haploinsufficiency, multiple sequential alterations targeting lymphoid development are central to leukemogenesis and contribute to the arrest in lymphoid maturation characteristic of ALL.

  10. miR-155 inhibits PU.1 expression, leading to Pax5 down-regulation and the initiation of the plasma cell differentiation pathway.

  11. restoring endogenous Pax5 expression in established B-ALL triggers immunophenotypic maturation and durable disease remission by engaging a transcriptional program reminiscent of normal B-cell differentiation

  12. Pax5 in GABAergic neurons is essential for normal ventricular development.

  13. results suggest that osteoblastic Pax5 would play a role in ovariectomy-induced bone loss through a mechanism relevant to the promotion of both osteoblastic bone formation and osteoclastic bone resorption in vivo

  14. Pax5 regulates Aicda transcription through its C-terminal-activation domain

  15. pax5 could positively regulate osteoblastic differentiation toward maturation in vitro, in addition to promoting bone formation and remodeling in vivo.

  16. Pax5 controls B-cell identity and function by regulating distinct target genes in early and late B lymphopoiesis.

  17. These data imply that PAX5 phosphorylation by the B-cell receptor signal is the initial event in plasma cell differentiation

  18. Data demonstrate that PAX5 regulates Csf1r in B cells by reducing the frequency of binding of the basal transcription machinery to the promoter.

  19. Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia

  20. Pax5 is shown to rapidly induce chromatin changes by recruiting chromatin-remodeling and histone-modifying complexes to its target genes.

Zebrafish Paired Box 5 (PAX5) Interaktionspartner

  1. pax5 works in conjunction with fgf3 and pax2a to establish and/or maintain the utricular macula and is essential for vestibular function.

PAX5 Antigen-Profil

Protein Überblick

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9\;14)(p13\;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

Genbezeichner und Symbole assoziert mit anti-Paired Box 5 (PAX5) Antikörper

  • paired box 5 (PAX5) Antikörper
  • paired box 5 L homeolog (pax5.L) Antikörper
  • paired box 5 (Pax5) Antikörper
  • paired box 5 (pax5) Antikörper
  • BSAP Antikörper
  • EBB-1 Antikörper
  • KLP Antikörper
  • noi Antikörper
  • Pax-5 Antikörper
  • pax2.1 Antikörper
  • pax2a Antikörper
  • PAX5 Antikörper
  • pax5-a Antikörper
  • paxzf-b Antikörper
  • Pax[Zf-b] Antikörper
  • RGD1565236 Antikörper

Bezeichner auf Proteinebene für anti-Paired Box 5 (PAX5) Antikörper

paired box 5 , paired box gene 5 (B-cell lineage specific activator) , paired box protein Pax-5 , paired box protein Pax-5-like , B-cell lineage specific activator , paired box homeotic gene 5 , paired domain gene 5 , transcription factor PAX 5 , XPax-5 , B-cell-specific transcription factor , Pax5 variant 1 , Pax5 variant 2 , No isthmus protein

GENE ID SPEZIES
716839 Macaca mulatta
747452 Pan troglodytes
100055252 Equus caballus
100389113 Callithrix jacchus
100457719 Pongo abelii
100481668 Ailuropoda melanoleuca
100586040 Nomascus leucogenys
5079 Homo sapiens
378499 Xenopus laevis
387330 Gallus gallus
612021 Canis lupus familiaris
500453 Rattus norvegicus
100520167 Sus scrofa
538371 Bos taurus
18507 Mus musculus
60636 Danio rerio
Ausgewählte Anbieter für anti-PAX5 (PAX5) Antikörper
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