anti-Paired Box 5 (PAX5) Antikörper

PAX5 encodes a member of the paired box (PAX) family of transcription factors. Zusätzlich bieten wir Ihnen PAX5 Proteine (7) und PAX5 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAX5 5079 Q02548
PAX5 500453  
PAX5 18507 Q02650
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Top anti-PAX5 Antikörper auf antikoerper-online.de

Showing 10 out of 254 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PAX5 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB PAX5 Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. PAX5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAX5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p) Flow cytometric analysis of rabbit anti-PAX-5 (SP34) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue). 7 mL Anmelden zum Anzeigen 2 bis 3 Tage
$308.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p) Flow cytometric analysis of rabbit anti-PAX-5 (SP34) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue). 1 mL Anmelden zum Anzeigen 2 bis 3 Tage
$705.00
Details
Human Maus Unkonjugiert IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10 ng), Green: Antigen (50ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded brain tumors tissues using PAX5 mouse mAb with DAB staining. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using PAX5 mouse mAb against Raji (1), and EVC-304 (2) cell lysate. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of Pax-5 on mouse spleen. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of anti-Pax-5 antibody. Immunofluorescent staining on SW-13 cells. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$154.07
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184804 staining (3µg/ml) of U937 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert WB Western blot analysis of PAX5 over-expressed 293 cell line, cotransfected with PAX5 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of PAX5 expression in transfected 293T cell line by PAX5 monoclonal antibody (M01), clone 8F9. Lane 1: PAX5 transfected lysate(42.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from 293 cells, using Pax-5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details

PAX5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PAX5 Antikörper

  1. Human Monoclonal PAX5 Primary Antibody für IHC (p) - ABIN1687422 : Steinert, Schenkel, Fraser, Beura, Manlove, Igyártó, Southern, Masopust: Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance. in Cell 2015 (PubMed)
    Show all 7 Pubmed References

  2. Human Monoclonal PAX5 Primary Antibody für FACS, IHC (p) - ABIN1687411 : Zanelli, Valli, Capodanno, Ragazzi, Ascani: Anaplastic lymphoma kinase-positive large B-cell lymphoma: description of a case with an unexpected clinical outcome. in International journal of surgical pathology 2015 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal PAX5 Primary Antibody für IF, IP - ABIN968220 : Adams, Dörfler, Aguzzi, Kozmik, Urbánek, Maurer-Fogy, Busslinger: Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. in Genes & development 1992 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal PAX5 Primary Antibody für IF, IP - ABIN968219 : Foss, Reusch, Demel, Lenz, Anagnostopoulos, Hummel, Stein: Frequent expression of the B-cell-specific activator protein in Reed-Sternberg cells of classical Hodgkin's disease provides further evidence for its B-cell origin. in Blood 1999 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal PAX5 Primary Antibody für IHC, ELISA - ABIN1098104 : OBrien, Morin, Ouellette, Robichaud: The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease. in Cancer research 2011 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal PAX5 Primary Antibody für ELISA, WB - ABIN969552 : Coyaud, Struski, Prade, Familiades, Eichner, Quelen, Bousquet, Mugneret, Talmant, Pages, Lefebvre, Penther, Lippert, Nadal, Taviaux, Poppe, Luquet, Baranger, Eclache, Radford, Barin, Mozziconacci et al.: Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study. ... in Blood 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen PAX5 Interaktionspartner

Human Paired Box 5 (PAX5) Interaktionspartner

  1. These findings suggested that pax5 is critically important for the proliferation and survival of pre-B cells.

  2. a mechanism of transcriptional regulation mediated by p27 (zeige PAK2 Antikörper), Pax5, and PCAF (zeige KAT2B Antikörper)

  3. Data show that paired box gene 5 (B-cell lineage specific activator) protein (Pax-5) induces E-cadherin (zeige CDH1 Antikörper) expression in breast cancer cells.

  4. a new function of PAX5 in regulating RIP1 (zeige UQCRFS1 Antikörper) and RIP2 (zeige ARHGEF28 Antikörper) activation, which is at least involved in chemotherapeutic drug resistance in B-lymphoproliferative disorders, is reported.

  5. PAX5-KIDINS220 (zeige KIDINS220 Antikörper) fusion is associated with Philadelphia-like acute lymphoblastic leukemia.

  6. this study shows that Pax5 expression is lower in antibody-secreting cells than in naive B cells or plasmablasts

  7. The histological observations suggested that the patients represent diverse cases of NHL (zeige RTEL1 Antikörper) like mature B-cell type, mature T-cell type and high grade diffuse B-cell type NHL (zeige RTEL1 Antikörper). The findings indicate that patients with NHL (zeige RTEL1 Antikörper) may also be analyzed for status of PAX5, CD19 (zeige CD19 Antikörper) and ZAP70 (zeige ZAP70 Antikörper), and their transcriptional and post-translational variants for the differential diagnosis of NHL (zeige RTEL1 Antikörper) and therapy.

  8. B cell receptor signaling component, SYK (zeige SYK Antikörper), caused PAX5 tyrosine phosphorylation in vitro and in cells. Transcriptional repression on the BLIMP1 (zeige PRDM1 Antikörper) promoter by PAX5 was attenuated by this phosphorylation.

  9. PAX5 haploinsufficiency promotes tumorigenesis and may be related to genomic instability, immune tolerance, and tumor pathways

  10. FISH studies showed false-negative results in 10, 40, and 28% of the samples tested for the IKZF1 (zeige IKZF1 Antikörper),PAX5, and CDKN2A (zeige CDKN2A Antikörper)/B gene deletions, respectively. The PAX5 and IKZF1 (zeige IKZF1 Antikörper) abnormalities are highly specific to B (zeige TDO2 Antikörper)-ALL and can be used as diagnostic markers

Xenopus laevis Paired Box 5 (PAX5) Interaktionspartner

  1. Pax5 transcription factor cooperates in patterning the Xenopus brain.

Mouse (Murine) Paired Box 5 (PAX5) Interaktionspartner

  1. identify Pax5 and cyclin D1 (zeige CCND1 Antikörper) as Zfp521 (zeige ZNF521 Antikörper) target genes

  2. Together with similar observations made in human PAX5-ETV6 (zeige ETV6 Antikörper)(+) B-ALLs, these data identified PAX5-ETV6 (zeige ETV6 Antikörper) fusion as a potent oncoprotein that drives B-cell leukemia development.

  3. PAX5 was found to be an epigenetically inactivated tumor suppressor that inhibited non-small-cell lung proliferation and metastasis, through down-regulating the beta-catenin (zeige CTNNB1 Antikörper) pathway and up-regulating GADD45G (zeige GADD45G Antikörper) expression.

  4. Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in mantle cell lymphoma independent of CCND1 (zeige CCND1 Antikörper).

  5. Spleen-specific isoform of Pax5 and Ataxin-7 (zeige ATXN7 Antikörper) can be considered as spleen-specific unique molecular markers for the evaluation of splenomegaly and lympho-proliferative disorders.

  6. Pax5 and Ebf1 (zeige EBF1 Antikörper) collaborate to modulate the transcriptional response to Notch (zeige NOTCH1 Antikörper) signaling, and their combined heterozygous loss allows for T-lineage conversion of B cell progenitors.

  7. a dramatic increase in the frequency of pro-B cell leukemia was observed in mice with combined heterozygous mutations in the Ebf1 (zeige EBF1 Antikörper) and Pax5 genes, revealing a synergistic effect of combined dose reduction of these proteins

  8. These results show that in contrast to simple Pax5 haploinsufficiency, multiple sequential alterations targeting lymphoid development are central to leukemogenesis and contribute to the arrest in lymphoid maturation characteristic of ALL.

  9. miR (zeige MLXIP Antikörper)-155 inhibits PU.1 expression, leading to Pax5 down-regulation and the initiation of the plasma cell differentiation pathway.

  10. restoring endogenous Pax5 expression in established B-ALL triggers immunophenotypic maturation and durable disease remission by engaging a transcriptional program reminiscent of normal B-cell differentiation

Zebrafish Paired Box 5 (PAX5) Interaktionspartner

  1. pax5 works in conjunction with fgf3 (zeige FGF3 Antikörper) and pax2a to establish and/or maintain the utricular macula and is essential for vestibular function.

PAX5 Antigen-Profil

Protein Überblick

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9\;14)(p13\;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

Genbezeichner und Symbole assoziert mit anti-Paired Box 5 (PAX5) Antikörper

  • paired box 5 (PAX5) Antikörper
  • paired box 5 L homeolog (pax5.L) Antikörper
  • paired box 5 (Pax5) Antikörper
  • paired box 5 (pax5) Antikörper
  • BSAP Antikörper
  • EBB-1 Antikörper
  • KLP Antikörper
  • noi Antikörper
  • Pax-5 Antikörper
  • pax2.1 Antikörper
  • pax2a Antikörper
  • PAX5 Antikörper
  • pax5-a Antikörper
  • paxzf-b Antikörper
  • Pax[Zf-b] Antikörper
  • RGD1565236 Antikörper

Bezeichner auf Proteinebene für anti-Paired Box 5 (PAX5) Antikörper

paired box 5 , paired box gene 5 (B-cell lineage specific activator) , paired box protein Pax-5 , paired box protein Pax-5-like , B-cell lineage specific activator , paired box homeotic gene 5 , paired domain gene 5 , transcription factor PAX 5 , XPax-5 , B-cell-specific transcription factor , Pax5 variant 1 , Pax5 variant 2 , No isthmus protein

GENE ID SPEZIES
716839 Macaca mulatta
747452 Pan troglodytes
100055252 Equus caballus
100389113 Callithrix jacchus
100457719 Pongo abelii
100481668 Ailuropoda melanoleuca
100586040 Nomascus leucogenys
5079 Homo sapiens
378499 Xenopus laevis
387330 Gallus gallus
612021 Canis lupus familiaris
500453 Rattus norvegicus
100520167 Sus scrofa
538371 Bos taurus
18507 Mus musculus
60636 Danio rerio
Ausgewählte Anbieter für anti-PAX5 (PAX5) Antikörper
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