anti-DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Antikörper

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Zusätzlich bieten wir Ihnen DNA (Cytosine-5-)-Methyltransferase 3 Like Proteine (12) und DNA (Cytosine-5-)-Methyltransferase 3 Like Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
TRDMT1 54427 Q9CWR8
TRDMT1 29947 Q9UJW3
TRDMT1 309680 Q1LZ50
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Top anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Antikörper auf antikoerper-online.de

Showing 10 out of 224 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert AA, ICC, IF, IHC, IP, WB SMC 341DNMT3LRat Tissue Mix Western Blotting. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$383.90
Details
Human Kaninchen Unkonjugiert ChIP, ELISA, ICC, IF, IHC, IP, WB Western blot analysis of Hela whole cell lysates, using DNMT3L Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277187 at 1/100 staining Mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using DNMT3L mAb against human DNMT3L (AA: 147-386) recombinant protein. (Expected MW is 53.9 kDa) 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$561.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Mouse Dnmt3L Antibody (ABIN387907) in Hela cell line lysates (35 µg/lane). Dnmt3l (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Dnmt3L-R322 (ABIN387892) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the DNMT3L antibody detected the DNMT3L protein (arrow). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus HRP AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$422.40
Details
Human Maus FITC AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$426.80
Details
Human Maus Alkaline Phosphatase (AP) AA, ICC, IF, IHC, IP, WB Immunohistochemistry analysis using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Lower layers of the epidermis have positive cell staining in the cytoplasm. Western Blot analysis of Human tissue lysate showing detection of Dnmt3L protein using Mouse Anti-Dnmt3L Monoclonal Antibody, Clone S117-9 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Dnmt3L Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$429.00
Details

Am meisten referenzierte anti-DNA (Cytosine-5-)-Methyltransferase 3 Like Antikörper

  1. Mammalian Monoclonal TRDMT1 Primary Antibody für ISt, IHC - ABIN1304620 : Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: Community resources and technologies developed through the NIH Roadmap Epigenomics Program. in Methods in molecular biology (Clifton, N.J.) 2014 (PubMed)

  2. Human Polyclonal TRDMT1 Primary Antibody für IHC (p), WB - ABIN387892 : Chedin, Lieber, Hsieh: The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal TRDMT1 Primary Antibody für WB - ABIN2668677 : Ajj, Chesnel, Pinel, Plenat, Flament, Dumond: An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism. in PLoS ONE 2013 (PubMed)

  4. Human Polyclonal TRDMT1 Primary Antibody für IHC (p), WB - ABIN4305755 : Bonnin, Belville, Chiambaretta, Sapin, Blanchon: DNA methyl transferases are differentially expressed in the human anterior eye segment. in Acta ophthalmologica 2014 (PubMed)

Weitere Antikörper gegen DNA (Cytosine-5-)-Methyltransferase 3 Like Interaktionspartner

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Interaktionspartner

  1. The Sirt1 (zeige SIRT1 Antikörper) protein suppressed transcription of Dnmt3l.

  2. The Dnmt3l mutation greatly reduced DNA methylation (zeige HELLS Antikörper) levels at most retrotransposons, but its impact on their RNA abundance was limited in prospermatogonia. In Pld6 (zeige PLD6 Antikörper) mutant germ cells, although only a few retrotransposons exhibited reduced DNA methylation (zeige HELLS Antikörper), many showed increased expression at the RNA level.

  3. Dnmt3l-KO donor cells may offer a more permissive epigenetic state that is beneficial for Nuclear transfer reprogramming

  4. By interacting with TRIM28 (zeige TRIM28 Antikörper), DNMT3L can attract various enzymes to form a DNMT3L-induced repressive complex to remove active marks and add repressive marks to histone proteins.

  5. Hypomethylation of highly methylated CpG islands was caused by the downregulation of Dnmt3L and Dnmt3a (zeige DNMT3A Antikörper) due to hepatitis B X-protein bound to their promoters.

  6. DNMT3L is required to delicately balance the cycling and quiescence of spermatogonial progenitor cells

  7. Study demonstrates that Dnmt3L interacts with the Polycomb (zeige CBX2 Antikörper) PRC2 complex in competition with the DNA methyltransferases Dnmt3a (zeige DNMT3A Antikörper) and Dnmt3b (zeige DNMT3B Antikörper) to maintain low methylation levels at the Histone 3 H3K27me3 regions.

  8. Data indicate that expression of Dnmt3a (zeige DNMT3A Antikörper), Dnmt3b (zeige DNMT3B Antikörper), Dnmt3L as well as maintenance Dnmt1o (zeige DNMT1 Antikörper) in oocytes and zygotes was not disrupted.

  9. Reduced expression of DNMT3L in male germ cells, associated with haploinsufficiency of the paternal-effect gene Dnmt3L, results in abnormal hypomethylation of prenatal germline progenitor cells.

  10. The maternal store of Dnmt3L is not involved in embryonic de novo methylation.

Human DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Interaktionspartner

  1. DNMT3L overexpression is associated with Down syndrome.

  2. the present study has demonstrated that variations in the DNMT3L gene do not contribute to stage I-II endometriosis-associated infertility.

  3. DNMT3L rs2070565 (genotype P = 0.007, allele P = 0.0026) confers an increased risk of developing schizophrenia at an early age in individuals with family history.

  4. crystal structures of DNMT3A (zeige DNMT3A Antikörper)-DNMT3L (autoinhibitory form) and DNMT3A (zeige DNMT3A Antikörper)-DNMT3L-H3 (active form) complexes at 3.82 and 2.90 A resolution, respectively

  5. DNMT3L can address DNMT3A (zeige DNMT3A Antikörper)/B to specific sites by directly interacting with TFs that do not directly interact with DNMT3A (zeige DNMT3A Antikörper)/B

  6. CpG island encompassing the promoter and first exon of human DNMT3L gene is a PcG/TrX (zeige VAC14 Antikörper) response element

  7. DNMT3L is one of the key players in de novo DNA methylation (zeige HELLS Antikörper) of imprinting control elements and retrotransposons, which occurs after genome-wide epigenetic erasure during germ cell development. (Review)

  8. SNP rs2070565, as well as haplotypes AAA (zeige APP Antikörper) and GAA (zeige GAA Antikörper), may be associated with male infertility; DNMT3L may contribute to azoospermia susceptibility in humans

  9. Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis.

  10. mutation analysis of SYCP3 (zeige SYCP3 Antikörper), DNMT3L and MSH4 (zeige MSH4 Antikörper) in patients with maturation arrest of spermatogenesis and couples with recurrent miscarriages.

DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1) Antigen-Profil

Protein Überblick

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit TRDMT1

  • DNA methyltransferase 3 like (DNMT3L) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l) Antikörper
  • DNA methyltransferase 3 like (Dnmt3l) Antikörper
  • D6Ertd14e Antikörper
  • DNMT3L Antikörper
  • ecat7 Antikörper

Bezeichner auf Proteinebene für TRDMT1

DNA (cytosine-5-)-methyltransferase 3-like , cytosine-5-methyltransferase 3-like protein , DNA (cytosine-5)-methyltransferase 3-like , human cytosine-5-methyltransferase 3-like protein

GENE ID SPEZIES
100050680 Equus caballus
470099 Pan troglodytes
613785 Bos taurus
608536 Canis lupus familiaris
54427 Mus musculus
29947 Homo sapiens
309680 Rattus norvegicus
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