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DNMT3L Antikörper (AA 147-386)

TRDMT1 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2D10H11 unconjugated
Produktnummer ABIN5542515
  • Target Alle DNMT3L (TRDMT1) Antikörper anzeigen
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    Bindungsspezifität
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-386
    Reaktivität
    • 72
    • 17
    • 2
    • 1
    Human
    Wirt
    • 72
    • 5
    Maus
    Klonalität
    • 74
    • 3
    Monoklonal
    Konjugat
    • 34
    • 8
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNMT3L Antikörper ist unkonjugiert
    Applikation
    • 70
    • 42
    • 20
    • 13
    • 13
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. coli.
    Klon
    2D10H11
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
    Andere Bezeichnung
    DNMT3L (TRDMT1 Produkte)
    Synonyme
    DNMT3L antikoerper, D6Ertd14e antikoerper, ecat7 antikoerper, DNA methyltransferase 3 like antikoerper, DNA (cytosine-5-)-methyltransferase 3-like antikoerper, DNMT3L antikoerper, Dnmt3l antikoerper
    Hintergrund
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,
    Molekulargewicht
    43.6 kDa
    Gen-ID
    29947
    HGNC
    29947
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