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DNMT3L Produkte

(DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012].

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Ausgewählte DNMT3L Kategorien

DNMT3L Antikörper

High quality antibodies with extensive validation data.

DNMT3L ELISA Kits

Reliable ELISA kits for a wide range of species.

DNMT3L Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DNMT3L Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN5542515
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IP
Validierungen
  • (5)
Kat. Nr. ABIN526180
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7260352
Menge 200 μL
Datenblatt Datenblatt

Empfohlene DNMT3L ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960699
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN4993275
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN2947075
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DNMT3L Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122681
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122680
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351871
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DNMT3L Produkten

Das, Chai, Kim, Lee, Park, Jung, Chai: "Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands." in: BMC genomics, Vol. 16, pp. 517, (2016) (PubMed).

Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).

Bonnin, Belville, Chiambaretta, Sapin, Blanchon: "DNA methyl transferases are differentially expressed in the human anterior eye segment." in: Acta ophthalmologica, Vol. 92, Issue 5, pp. e366-71, (2014) (PubMed).

Ajj, Chesnel, Pinel, Plenat, Flament, Dumond: "An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism." in: PLoS ONE, Vol. 8, Issue 4, pp. e61758, (2013) (PubMed).

Yu, Thieu, Kaplan: "Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation." in: The EMBO journal, Vol. 26, Issue 8, pp. 2052-60, (2007) (PubMed).

Deplus, Brenner, Burgers, Putmans, Kouzarides, de Launoit, Fuks: "Dnmt3L is a transcriptional repressor that recruits histone deacetylase." in: Nucleic acids research, Vol. 30, Issue 17, pp. 3831-8, (2002) (PubMed).

Chedin, Lieber, Hsieh: "The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16916-21, (2002) (PubMed).

Kierszenbaum: "Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths." in: Molecular reproduction and development, Vol. 63, Issue 3, pp. 269-72, (2002) (PubMed).

Okazaki, Furuno, Kasukawa, Adachi, Bono, Kondo, Nikaido, Osato, Saito, Suzuki, Yamanaka, Kiyosawa, Yagi, Tomaru, Hasegawa, Nogami, Schönbach, Gojobori, Baldarelli, Hill, Bult, Hume, Quackenbush et al.: "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. ..." in: Nature, Vol. 420, Issue 6915, pp. 563-73, (2002) (PubMed).

Aapola, Lyle, Krohn, Antonarakis, Peterson: "Isolation and initial characterization of the mouse Dnmt3l gene." in: Cytogenetics and cell genetics, Vol. 92, Issue 1-2, pp. 122-6, (2001) (PubMed).

Synonyme und alternative Namen zu DNMT3L

DNA methyltransferase 3 like (DNMT3L), DNA (cytosine-5-)-methyltransferase 3-like (Dnmt3l), DNA methyltransferase 3 like (Dnmt3l), D6Ertd14e, DNMT3L, ecat7

Bezeichner auf Proteinebene für DNMT3L

  • DNA (cytosine-5-)-methyltransferase 3-like
  • cytosine-5-methyltransferase 3-like protein
  • DNA (cytosine-5)-methyltransferase 3-like
  • human cytosine-5-methyltransferase 3-like protein
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