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DNMT3L Antikörper (DNA (Cytosine-5-)-Methyltransferase 3 Like) AA 152-164 Primary Antibody

TRDMT1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129584
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle DNMT3L (TRDMT1) Antikörper anzeigen
    DNMT3L (TRDMT1)
    Bindungsspezifität
    • 17
    • 15
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 152-164
    Reaktivität
    • 81
    • 20
    • 2
    • 1
    Human
    Wirt
    • 79
    • 8
    Kaninchen
    Klonalität
    • 81
    • 6
    Polyklonal
    Konjugat
    • 36
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNMT3L Antikörper ist unkonjugiert
    Applikation
    • 68
    • 48
    • 24
    • 13
    • 13
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 152-164 of Human DNMT3L (DNA (cytosine-5-)-methyltransferase 3-like). DNMT3L is a nuclear protein with similarity to DNA methyltransferases.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays is unknown.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.11 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    DNMT3L (TRDMT1)
    Andere Bezeichnung
    DNMT3L (TRDMT1 Produkte)
    Synonyme
    DNMT3L, D6Ertd14e, ecat7, DNA methyltransferase 3 like, DNA (cytosine-5-)-methyltransferase 3-like, DNMT3L, Dnmt3l
    Hintergrund
    DNMT 3L is a nuclear protein that has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltrans-ferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1.
    Synonyms: DNA (cytosine-5)-methyltransferase 3-like DNMT3L
    Gen-ID
    29947
    NCBI Accession
    NP_787063
    UniProt
    Q9UJW3
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