MAP3K7 Antikörper (pSer192)

Produktnummer ABIN358312

Produktdetails anti-MAP3K7 Antikörper

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Bindungsspezifität: pSer192

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K7 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects TAK1 / MAP3K7 pSer192.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse (100 % Antigen Homology).
Species reactivity (tested):Human.

Aufreinigung: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification

Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser192 of Human MAP3K7. Genename: MAP3K7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Dot Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Andere Bezeichnung: TAK1 / MAP3K7 (MAP3K7 Produkte)

Synonyme: si:ch211-225h9.1 antikoerper, zgc:110612 antikoerper, Tak1 antikoerper, MEKK7 antikoerper, TAK1 antikoerper, TGF1a antikoerper, B430101B05 antikoerper, C87327 antikoerper, mitogen-activated protein kinase kinase kinase 7 antikoerper, mitogen activated protein kinase kinase kinase 7 antikoerper, map3k7 antikoerper, Map3k7 antikoerper, MAP3K7 antikoerper

Hintergrund: MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1

Molekulargewicht: 67196 Da

Gen-ID: 6885, 9606

UniProt: O43318

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway