p53 Antikörper (Tumor Protein P53) (C-Term)

Details for Product anti-TP53 Antibody No. ABIN2792141, Anbieter: Anmelden zum Anzeigen
Antigen
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
C-Term
172
128
94
84
74
71
70
62
59
55
50
49
48
47
42
38
32
31
29
28
24
22
20
20
17
16
15
15
15
15
15
14
12
11
10
10
10
9
9
8
7
7
7
7
7
7
6
6
6
6
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Pferd, Human, Ratte (Rattus)
2428
519
425
188
127
94
87
84
35
23
19
18
17
16
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Kaninchen
1371
1170
7
3
1
1
1
1
Klonalität
Polyklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
81
78
65
55
49
48
34
34
26
26
25
25
25
25
25
24
24
24
23
22
22
21
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
1931
772
750
742
651
637
435
347
316
179
72
41
32
31
24
17
17
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TP53
Sequenz RELNEALELK DAQAGKEPGG SRAHSSHLKS KKGQSTSRHK KLMFKTEGPD
Homologie Horse: 93%, Human: 100%, Rat: 92%
Produktmerkmale This is a rabbit polyclonal antibody against TP53. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Andere Bezeichnung TP53 (TP53 Antibody Abstract)
Hintergrund TP53 acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
Alias Symbols: P53, LFS1, TRP53
Protein Size: 393
Molekulargewicht 44 kDa
Gen-ID 7157
NCBI Accession NM_000546, NP_000537
UniProt P04637
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 393 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2792141) Rabbit Anti-TP53 antibody Catalog Number: AVARP02055 Paraffin Embedded Tissue: Human...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (C-Term) antibody (ABIN2792141) WB Suggested Anti-TP53 Antibody Titration: 0.5 ug/ml Positive Control: DU145 CELLS T...
Allgemeine Veröffentlichungen Zakut-Houri, Bienz-Tadmor, Givol, Oren: "Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells." in: The EMBO journal, Vol. 4, Issue 5, pp. 1251-5, 1985 (PubMed).

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