p53 Produkte
(Tumor Protein P53 (TP53))
Kategorien
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
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Ausgewählte p53 Kategorien
p53 Antikörper
High quality antibodies with extensive validation data.
p53 ELISA Kits
Reliable ELISA kits for a wide range of species.
p53 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene p53 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), IP, ICC
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN2854816
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), IP, ICC, ChIP
Validierungen
- (1)
- (8)
Kat. Nr.
ABIN2855525
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (1)
- (12)
Kat. Nr.
ABIN6256312
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene p53 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960305
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960306
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960307
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene p53 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1323380
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (3)
Kat. Nr.
ABIN2669713
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN2734068
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren p53 Produkten
: "The implication of autoantibodies in early diagnosis and monitoring of plasmonic photothermal therapy in the treatment of feline mammary carcinoma." in: Scientific reports, Vol. 11, Issue 1, pp. 10441, (2021) (PubMed).: "Tau affects P53 function and cell fate during the DNA damage response." in: Communications biology, Vol. 3, Issue 1, pp. 245, (2021) (PubMed).
: "Cynaropicrin Induces Cell Cycle Arrest and Apoptosis by Inhibiting PKM2 to Cause DNA Damage and Mitochondrial Fission in A549 Cells." in: Journal of agricultural and food chemistry, Vol. 69, Issue 45, pp. 13557-13567, (2021) (PubMed).
: "Garlic Extract Alleviates Trastuzumab-Induced Hepatotoxicity in Rats Through Its Antioxidant, Anti-Inflammatory, and Antihyperlipidemic Effects." in: Journal of inflammation research, Vol. 14, pp. 6305-6316, (2021) (PubMed).
: "UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish." in: Animals : an open access journal from MDPI, Vol. 10, Issue 6, (2020) (PubMed).
: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).
: "Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes." in: Biochemical and biophysical research communications, Vol. 517, Issue 2, pp. 216-220, (2020) (PubMed).
: "Suitability of MDA, 8-OHdG and wild-type p53 as genotoxic biomarkers in metal (Co, Ni and Cr) exposed dental technicians: a cross-sectional study." in: BMC oral health, Vol. 20, Issue 1, pp. 65, (2020) (PubMed).
: "Discovery and characterization of a novel splice variant of the p53 tumor suppressor gene in a human T cell leukemia cellline." in: International journal of clinical and experimental pathology, Vol. 13, Issue 5, pp. 1121-1135, (2020) (PubMed).
: "Synergistic Action of 1,2-Epoxy-3 (3- (3,4-dimethoxyphenyl)- 4H-1-benzopiyran-4-on) Propane with Doxorubicin and Cisplatin through Increasing of p53, TIMP-3, and MicroRNA-34a in Cervical Cancer Cell ..." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 10, pp. 2955-2962, (2019) (PubMed).
Synonyme und alternative Namen zu p53
tumor protein p53 (TP53), cellular tumor antigen p53 (CpipJ_CPIJ002758), tumor protein p53 (Tp53), tumor protein p53 (tp53), transformation related protein 53 (Trp53), tumor protein p53 L homeolog (tp53.L), bbl, BCC7, bfy, bhy, brp53, drp53, etID22686.5, fb40d06, LFS1, p44, P53, p53, Tp53, tp53, TP53, TRP53, Trp53, wu:fb40d06, Xp53, zgc:111919Bezeichner auf Proteinebene für p53
- antigen NY-CO-13
- cellular tumor antigen p53
- p53 tumor suppressor
- phosphoprotein p53
- transformation-related protein 53
- tumor suppressor p53
- transformation related protein 53
- tumor protein p53 (Li-Fraumeni syndrome)
- p53 tumor suppressor phosphoprotein
- tumor protein 53
- tumor suppressor protein
- p53 cellular tumor antigen
- tumor supressor p53
- Tumor suppressor p53
- Cellular tumor antigen p53
- Li-Fraumeni syndrome
- tumor suppressor protein p53
- P53
- tumor suppressing protein
- tumor suppressor ortholog
- tumor supressor protein
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