P4HB Produkte
(Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
Kategorien
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008].
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Ausgewählte P4HB Kategorien
P4HB Antikörper
High quality antibodies with extensive validation data.
P4HB ELISA Kits
Reliable ELISA kits for a wide range of species.
P4HB Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene P4HB Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP, IF
Validierungen
- (6)
Kat. Nr.
ABIN950024
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC, IHC (p), IEM
Validierungen
- (6)
Kat. Nr.
ABIN2855054
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, FACS
Validierungen
- (6)
Kat. Nr.
ABIN6134876
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene P4HB ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969624
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958836
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1116747
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene P4HB Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313838
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124599
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320210
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren P4HB Produkten
: "Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles." in: International journal of molecular sciences, Vol. 20, Issue 17, (2020) (PubMed).: "Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas." in: Cell death & disease, Vol. 10, Issue 2, pp. 143, (2020) (PubMed).
: "A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome." in: Cell chemical biology, Vol. 25, Issue 5, pp. 634-643.e4, (2019) (PubMed).
: "LRP5 controls cardiac QT interval by modulating the metabolic homeostasis of L-type calcium channel." in: International journal of cardiology, Vol. 275, pp. 120-128, (2019) (PubMed).
: "Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum. ..." in: Cell, Vol. 176, Issue 6, pp. 1461-1476.e23, (2019) (PubMed).
: "Protein disulfide isomerase plasma levels in healthy humans reveal proteomic signatures involved in contrasting endothelial phenotypes." in: Redox biology, Vol. 22, pp. 101142, (2019) (PubMed).
: "GLUT10-Lacking in Arterial Tortuosity Syndrome-Is Localized to the Endoplasmic Reticulum of Human Fibroblasts." in: International journal of molecular sciences, Vol. 18, Issue 8, (2018) (PubMed).
: "Tumor-fibroblast interactions stimulate tumor vascularization by enhancing cytokine-driven production of MMP9 by tumor cells." in: Oncotarget, Vol. 8, Issue 22, pp. 35592-35608, (2017) (PubMed).
: "Myogenic potential of human alveolar mucosa derived cells." in: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 6, pp. 545-555, (2017) (PubMed).
: "Structure-function analyses of microsomal triglyceride transfer protein missense mutations in abetalipoproteinemia and hypobetalipoproteinemia subjects." in: Biochimica et biophysica acta, Vol. 1861, Issue 11, pp. 1623-1633, (2016) (PubMed).
Synonyme und alternative Namen zu P4HB
prolyl 4-hydroxylase subunit beta (P4HB), protein disulfide isomerase family A member 2 (PDIA2), prolyl 4-hydroxylase, beta polypeptide (P4hb), prolyl 4-hydroxylase subunit beta (P4hb), prolyl 4-hydroxylase, beta polypeptide (P4HB), protein disulfide isomerase family A member 2 L homeolog (pdia2.L), protein disulfide isomerase associated 2 (Pdia2), prolyl 4-hydroxylase subunit beta L homeolog (p4hb.L), protein disulfide-isomerase (LOC8281065), 1810041F13Rik, AI661267, DSI, ERBA2L, ERp59, GIT, P4Hbeta, p55, p58, PDA2, PDI, pdi, PDIA1, Pdia1, PDIP, Pdip, Pdipl, PDIR, PHDB, PO4DB, PO4HB, PROHB, Thbp, XPDIpBezeichner auf Proteinebene für P4HB
- cellular thyroid hormone-binding protein
- collagen prolyl 4-hydroxylase beta
- glutathione-insulin transhydrogenase
- p55
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
- prolyl 4-hydroxylase subunit beta
- protein disulfide isomerase family A, member 1
- protein disulfide isomerase-associated 1
- protein disulfide isomerase/oxidoreductase
- protein disulfide-isomerase
- protocollagen hydroxylase
- thyroid hormone-binding protein p55
- Rho GDP dissociation inhibitor gamma
- pancreas-specific protein disulfide isomerase
- pancreatic protein disulfide isomerase
- protein disulfide isomerase A2
- protein disulfide isomerase, pancreatic
- protein disulfide isomerase-associated 2
- protein disulfide-isomerase A2
- ER protein 59
- endoplasmic reticulum resident protein 59
- protein disulfide isomerase
- Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide)
- PDI (E.C.5.3.4.1)
- cellular thyroid hormone binding protein
- prolyl 4-hydroxylase beta polypeptide
- prolyl 4-hydroxylase, beta subunit
- Cellular thyroid hormone-binding protein
- Prolyl 4-hydroxylase subunit beta
- multifunctional thyroid hormone binding protein
- PDI
- protein disulfide isomerase (pancreas) like
- R-cognin
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase-associated 1)
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)
- retina cognin
- protein disulphide isomerase PDI
- p58
- prolyl 4-hydroxylase, beta polypeptide
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