P4HA1 Produkte
(Prolyl 4-Hydroxylase, alpha Polypeptide I (P4HA1))
Kategorien
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte P4HA1 Kategorien
P4HA1 Antikörper
High quality antibodies with extensive validation data.
P4HA1 ELISA Kits
Reliable ELISA kits for a wide range of species.
P4HA1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene P4HA1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN190847
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7164781
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN518574
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene P4HA1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969620
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969621
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958833
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene P4HA1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124598
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313832
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN3122720
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren P4HA1 Produkten
: "In vitro chondrogenic potency of surplus chondrocytes from autologous transplantation procedures does not predict short-term clinical outcomes." in: BMC musculoskeletal disorders, Vol. 20, Issue 1, pp. 19, (2019) (PubMed).: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).
: "Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 2, pp. 151-64, (2014) (PubMed).
: "Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse." in: American journal of physiology. Heart and circulatory physiology, Vol. 307, Issue 5, pp. H773-81, (2014) (PubMed).
: "Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10819-29, (2013) (PubMed).
: "Collagen prolyl hydroxylases are essential for breast cancer metastasis." in: Cancer research, Vol. 73, Issue 11, pp. 3285-96, (2013) (PubMed).
: "BBF2H7-mediated Sec23A pathway is required for endoplasmic reticulum-to-Golgi trafficking in dermal fibroblasts to promote collagen synthesis." in: The Journal of investigative dermatology, Vol. 132, Issue 8, pp. 2010-8, (2012) (PubMed).
: "Proteomic changes in articular cartilage of human endemic osteoarthritis in China." in: Proteomics, Vol. 11, Issue 14, pp. 2881-90, (2011) (PubMed).
: "Hypoxia potentiates microRNA-mediated gene silencing through posttranslational modification of Argonaute2." in: Molecular and cellular biology, Vol. 31, Issue 23, pp. 4760-74, (2011) (PubMed).
: "Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7067-78, (2010) (PubMed).
Synonyme und alternative Namen zu P4HA1
prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ000975), prolyl 4-hydroxylase subunit alpha-1 (CpipJ_CPIJ017131), prolyl 4-hydroxylase subunit alpha-1 (Tsp_03346), prolyl 4-hydroxylase subunit alpha-1 (Tsp_03347), prolyl 4-hydroxylase subunit alpha-1 (Tsp_15957), prolyl 4-hydroxylase subunit alpha 1 (P4HA1), procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (P4ha1), prolyl 4-hydroxylase subunit alpha 1 (P4ha1), AL022634, P4HA, P4ha, PHalphaIBezeichner auf Proteinebene für P4HA1
- prolyl 4-hydroxylase subunit alpha-1
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I
- prolyl 4-hydroxylase alpha subunit
- prolyl 4-hydroxylase, alpha I subunit
- 4-PH alpha-1
- procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1
- C-P4Halpha(I)
- collagen prolyl 4-hydroxylase alpha(I)
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
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