anti-WEE1 (WEE1) Antikörper

Bezeichnung:: anti-WEE1 Homolog (S. Pombe) Antikörper (WEE1)

Auf www.antikoerper-online.de finden Sie aktuell 158 WEE1 Homolog (S. Pombe) (WEE1) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen WEE1 Proteine (9) und WEE1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 184 WEE1 Produkte verfügbar.

Synonyme:: ATWEE1, F22D16.3, F22D16_3, GB19689, wee1, WEE1 kinase homolog, WEE1-KINASE, WEE1A, wee1b, WEE1hu, xwee1, xwee2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	WEE1	308937	Q63802
	WEE1	22390	P47810
	WEE1	7465	P30291
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-WEE1 (WEE1) Antikörper

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anti-Rat (Rattus) WEE1 Antikörper:

anti-Mouse (Murine) WEE1 Antikörper:

anti-Human WEE1 Antikörper:

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Verknüpfte Pathways mit anti-WEE1 Antikörper

M Phase

Weitere Produktkategorien zu WEE1 Antikörper

Am meisten referenzierte anti-WEE1 Antikörper

Human Polyclonal WEE1 Primary Antibody für IP, IHC - ABIN222939 : Caffarel, Sarrió, Palacios, Guzmán, Sánchez: Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. in Cancer research 2006 (PubMed)
Human Monoclonal WEE1 Primary Antibody für ELISA, WB - ABIN521378 : Yue, Zhen, Huang, Zheng, Feng, Jiang, Yang, Wu, Liu, Guo: Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells. in PLoS ONE 2016 (PubMed)
Human Polyclonal WEE1 Primary Antibody für DB, IHC (p) - ABIN389681 : Müller, Lutter, Püschel: Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. in Journal of cell science 2010 (PubMed)

Weitere Antikörper gegen WEE1 Interaktionspartner

Mouse (Murine) WEE1 Homolog (S. Pombe) (WEE1) Interaktionspartner

Morphine significantly downregulated the expression of miRNA-219-5p, which targets WEE1 to suppress Tyr15 expressions and activate Cdc2 (zeige CDK1 Antikörper), thus inhibiting the morphine-induced macrophage apoptosis.
Results revealed that WEE1 is indispensable for maintaining genomic stability and it functions as a haploinsufficient tumor suppressor.
Wee1 is directly or indirectly involved in the mechanism of the circadian rhythm-dependent changes in docetaxel-induced intestinal damage.
The induction of Wee1 under hypoxia was confirmed both at the mRNA and protein levels.
In this study, we found that the chromosomal wee1 gene is also down-regulated by KLF3 (zeige KLF3 Antikörper).
The regulation of Wee1 by SadA (zeige BRSK2 Antikörper) and SadB (zeige BRSK1 Antikörper) kinases is essential for the differentiation of polarized neurons.
Mammalian Wee1 plays a critical role in maintaining genome integrity and is essential for embryonic survival at the pre-implantation stage of mouse development.
expression of wee1 was directly regulated by the molecular components of the circadian clockwork in the regenerating liver
transcription repressive activity of TBP-related factor 2 (zeige TBPL1 Antikörper) to wee1 promoter needs association with the promoter and TFIIA (zeige GTF2A1 Antikörper)
the suppression of nuclear import of cyclin B1 (zeige CCNB1 Antikörper), the induction of Wee1 kinase activity, and the transient nuclear accumulation of p21(CIP1/WAF1 (zeige CDKN1A Antikörper)) may play important roles in the transient cell cycle delay in response to ionizing radiation

Human WEE1 Homolog (S. Pombe) (WEE1) Interaktionspartner

the data suggest the importance of WEE1 as an enabler of branching vascularisation in colorectal cancer liver metastases.
WEE1 is over-expressed and could enhance gastric cancer cell proliferation and metastasis
Wee1 is identified as a novel direct target of miR (zeige MLXIP Antikörper)-194. Ectopic expression of Wee1 at least in part overcomes the suppressive impacts of miR (zeige MLXIP Antikörper)-194 on the malignant phenotypes of human laryngeal squamous cell carcinoma
High WEE1 expression is associated with non-small cell lung cancer.
miR (zeige MLXIP Antikörper)-503 could function as an enhancer of radiation responses in laryngeal carcinoma cells by inhibiting WEE1
Data suggest that SMURF1 (zeige SMURF1 Antikörper) is required for S phase progression; SMURF1 (zeige SMURF1 Antikörper) promotes ubiquitination-dependent degradation of WEE1; these functions of SMURF1 (zeige SMURF1 Antikörper) appear to be linked and may be important in cell proliferation and tumorigenesis. (SMURF1 (zeige SMURF1 Antikörper) = SMAD specific E3 ubiquitin protein ligase 1 (zeige SMURF1 Antikörper); WEE1 = wee 1 homolog [S pombe] protein)
Date show that when Wee1 alone is inhibited, Chk1 (zeige CHEK1 Antikörper) suppresses CDC45 (zeige CDC45 Antikörper) loading and thereby limits the extent of unscheduled replication initiation and subsequent S-phase DNA damage, despite very high CDK (zeige CDK4 Antikörper)-activity.
we overexpressed CKS1B (zeige CKS1B Antikörper) in multiple cell lines and found increased sensitivity to PLK1 (zeige PLK1 Antikörper) knockdown and PLK1 (zeige PLK1 Antikörper) drug inhibition. Finally, combined inhibition of WEE1 and PLK1 (zeige PLK1 Antikörper) results in less apoptosis than predicted based on an additive model of the individual inhibitors, showing an epistatic interaction and confirming a prediction of the yeast data.
Wee1 staining intensity was a predictor of favorable metastasis-free and overall survival compared to strong intensity and no or weak staining
These results highlight the key role of WEE1 suppression to combat glioblastomas. Moreover, it showed beneficial possibilities of WEE1 suppression with different anticancer approaches for neurological malignancies.

Arabidopsis thaliana WEE1 Homolog (S. Pombe) (WEE1) Interaktionspartner

the identification of a second member of the RNase H2 complex, RNase H2B (zeige RNASEH2B Antikörper), being able to complement the root growth phenotype of WEE1(KO) plants, is reported.
mutant alleles of the genes encoding subunits of the ribonuclease H2 (RNase H2) complex, known for its role in removing ribonucleotides from DNA-RNA duplexes, were identified as suppressor mutants of WEE1 knockout plants.
The plant WEE1 kinase acquired an indirect developmental function that is important for meristem maintenance upon replication stress.
The WEE1 gene is not rate-limiting for cell cycle progression under normal growth conditions but is a critical target of the ATR (zeige ATR Antikörper)-ATM (zeige ATM Antikörper) signaling cascades that inhibit the cell cycle upon activation of the DNA integrity checkpoints.

WEE1 Antigen-Profil

Beschreibung des Gens

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Alternative names and synonyms associated with WEE1

WEE1 G2 checkpoint kinase (WEE1) Antikörper
WEE1 homolog 2 (wee2) Antikörper
Wee1 kinase (Wee1) Antikörper
wee1-like protein kinase (LOC551677) Antikörper
WEE1 G2 checkpoint kinase (Wee1) Antikörper
WEE 1 homolog 1 (S. pombe) (Wee1) Antikörper
WEE1-like kinase (WEE1) Antikörper

ATWEE1 Antikörper
F22D16.3 Antikörper
F22D16_3 Antikörper
GB19689 Antikörper
wee1 Antikörper
WEE1 kinase homolog Antikörper
WEE1-KINASE Antikörper
WEE1A Antikörper
wee1b Antikörper
WEE1hu Antikörper
xwee1 Antikörper
xwee2 Antikörper

Bezeichner auf Proteinebene für WEE1

WEE1 homolog (S. pombe) , wee1-like protein kinase 2 , Wee1 kinase , Wee1-like protein kinase , wee1 tyrosine kinase , wee1-like protein kinase , wee1A kinase , WEE1 tyrosine kinase , WEE1+ homolog

GENE ID	SPEZIES
100071182	Equus caballus
100125126	Xenopus (Silurana) tropicalis
100544287	Meleagris gallopavo
5895039	Monosiga brevicollis MX1
551677	Apis mellifera
308937	Rattus norvegicus
22390	Mus musculus
7465	Homo sapiens
100345730	Oryctolagus cuniculus
423045	Gallus gallus
476847	Canis lupus familiaris
100521487	Sus scrofa
540322	Bos taurus
839453	Arabidopsis thaliana

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