anti-Rind (Kuh) TLR9 Antikörper für Western Blotting

Recommended TLR9 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Toll-Like Receptor 9 (TLR9) Antikörper
  • CD289
  • toll like receptor 9
  • toll-like receptor 9
  • TLR9
  • Tlr9
Epitop
N-Term
39
32
15
13
13
10
8
7
7
6
6
6
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
273
166
55
36
23
21
7
4
3
2
1
1
1
1
1
Wirt
Kaninchen
144
132
55
14
4
3
Klonalität
Polyklonal
Konjugat
Dieser TLR9 Antikörper ist unkonjugiert
28
28
19
9
7
6
6
6
6
6
4
4
4
4
3
3
3
3
3
2
2
2
1
1
Applikation
Western Blotting (WB)
243
190
134
109
91
39
37
35
15
7
6
6
6
5
5
3
3
3
2
Optionen
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Bilder

Produktnummer ABIN2777826
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN467852 WB Rabbit AA 251-300 Anmelden zum Anzeigen Polyclonal 0

General

Antigen Toll-Like Receptor 9 (TLR9) Antikörper
Epitop N-Term
(39), (32), (15), (13), (13), (10), (8), (7), (7), (6), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
(273), (166), (55), (36), (23), (21), (7), (4), (3), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(144), (132), (55), (14), (4), (3)
Klonalität
Polyklonal
Konjugat Dieser TLR9 Antikörper ist unkonjugiert
(28), (28), (19), (9), (7), (6), (6), (6), (6), (6), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Applikation Western Blotting (WB)
(243), (190), (134), (109), (91), (39), (37), (35), (15), (7), (6), (6), (6), (5), (5), (3), (3), (3), (2)
Pubmed 1 Publikation vorhanden
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Produktdetails anti-TLR9 Antikörper

Target Details TLR9 Anwendungsinformationen Handhabung Referenzen für anti-TLR9 Antikörper (ABIN2777826) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985142.
Sequenz VGGNCRRCDH APNPCMECPR HFPQLHPDTF SHLSRLEGLV LKDSSLSWLN
Homologie Cow: 100%, Dog: 85%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%
Produktmerkmale This is a rabbit polyclonal antibody against TLR9. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TLR9
Plasmids, Primers & others

Target Details TLR9

Produktdetails anti-TLR9 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TLR9 Antikörper (ABIN2777826) Bilder zurück nach oben
Antigen
Andere Bezeichnung TLR9 (TLR9 Antibody Abstract)
Hintergrund TLR9 participates in the innate immune response to microbial agents. TLR9 detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. TLR9 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CD289
Protein Interaction Partner: SYK, BTK, STK11IP, UNC93B1, UGGT1, TOLLIP, PALD1, TRAF3, CLGN, TRIM69, TBK1, STUB1, TRAF6, SRC, PRKCZ, MYD88, IRAK1, HSPA8, RNF216, SIGIRR, MAPK8IP3, TLR1, HRAS,
Protein Size: 1032
Molekulargewicht 113 kDa
Gen-ID 54106
NCBI Accession NM_017442, NP_059138
UniProt Q9NR96
Pathways TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-TLR9 Antikörper Target Details TLR9 Handhabung Referenzen für anti-TLR9 Antikörper (ABIN2777826) Bilder zurück nach oben
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1032 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TLR9 Antikörper Target Details TLR9 Anwendungsinformationen Referenzen für anti-TLR9 Antikörper (ABIN2777826) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TLR9 Antikörper (ABIN2777826)

Produktdetails anti-TLR9 Antikörper Target Details TLR9 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Ramirez-Ortiz, Specht, Wang, Lee, Bartholomeu, Gazzinelli, Levitz: "Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA." in: Infection and immunity, Vol. 76, Issue 5, pp. 2123-9, 2008

Bilder

Produktdetails anti-TLR9 Antikörper Target Details TLR9 Anwendungsinformationen Handhabung Referenzen für anti-TLR9 Antikörper (ABIN2777826) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Toll-Like Receptor 9 (TLR9) (N-Term) antibody (ABIN2777826) WB Suggested Anti-TLR9 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive...