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anti-Human ATF6B Antikörper:
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Hamster Polyclonal ATF6B Primary Antibody für WB - ABIN651294
Guan, Wang, Li, Xu, Yang, Shen: N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha. in Journal of cellular biochemistry 2009
Show all 2 Pubmed References
Human Polyclonal ATF6B Primary Antibody für IHC, IHC (p) - ABIN4282059
Pappas, Liang, Kim, Rivera, Dauer: TorsinA dysfunction causes persistent neuronal nuclear pore defects. in Human molecular genetics 2019
ATF4 and ATF6beta act synergistically in the negative regulation of placental growth factor mRNA expression
unglycosylated ATF6beta may directly facilitate the expression of ERSR genes by losing its repressor function to ATF6alpha
Metaphyseal chondrodysplasia Schmid type disease severity in mice is increased by ATF6alpha ablation and decreased by ATF6beta ablation triggered by mutations in collagen X.
Toxoplasma virulence factor ROP18 inactivates host innate and adaptive immune responses by targeting ATF6beta.
interference with ATF6beta-dependent immune responses is a novel pathogenic mechanism induced by ROP18
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum\; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
cAMP responsive element binding protein-like 1
, activating transcription factor 6 beta
, cyclic AMP-dependent transcription factor ATF-6 beta
, cyclic AMP-dependent transcription factor ATF-6 beta-like
, Creb-related protein
, cAMP response element-binding protein-related protein
, cAMP-dependent transcription factor ATF-6 beta
, cAMP-responsive element-binding protein-like 1
, protein G13
, cAMP responsive elment binding protein-like 1
, cAMP response element binding protein-related protein