ATF6B Antikörper (AA 560-589)
Kurzübersicht für ATF6B Antikörper (AA 560-589) (ABIN3029852)
Target
Alle ATF6B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 560-589
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Verwendungszweck
- ATF6 beta Antibody
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 560-589 from the human protein was used as the immunogen for this ATF6 beta antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the ATF6 beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the ATF6 beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
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Andere Bezeichnung
- ATF6 beta
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Hintergrund
- ATF6 beta is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.
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UniProt
- Q99941
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Pathways
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
Target
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