anti-Kaninchen TGIF1 Antikörper für Western Blotting

Recommended TGIF1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
TGFB-Induced Factor Homeobox 1 (TGIF1) Antikörper
  • HPE4
  • TGIF
  • IZUMO
  • AA959811
  • AI462167
  • Tgif
  • Tfig
  • fa06h05
  • fb33g11
  • zgc:55852
  • wu:fa06h05
  • wu:fb33g11
  • hpe4
  • tgif
  • tgif1
  • TGFB induced factor homeobox 1
  • izumo sperm-egg fusion 1
  • TGFB-induced factor homeobox 1
  • TGFB induced factor homeobox 1 S homeolog
  • TGIF1
  • IZUMO1
  • Tgif1
  • tgif1
  • tgif1.S
Epitop
C-Term
14
10
8
7
6
5
4
4
3
3
3
3
3
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
73
7
2
1
1
1
1
1
Wirt
Kaninchen
45
27
1
1
Klonalität
Polyklonal
Konjugat
Dieser TGIF1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
65
24
4
4
4
3
2
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2784526
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN321857 WB Rabbit IgG AA 324-373 Anmelden zum Anzeigen Polyclonal 0

General

Antigen TGFB-Induced Factor Homeobox 1 (TGIF1) Antikörper
Epitop C-Term
(14), (10), (8), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
(73), (7), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(45), (27), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser TGIF1 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Western Blotting (WB)
(65), (24), (4), (4), (4), (3), (2), (2), (1)
Pubmed 1 Publikation vorhanden
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Produktdetails anti-TGIF1 Antikörper

Target Details TGIF1 Anwendungsinformationen Handhabung Referenzen für anti-TGIF1 Antikörper (ABIN2784526) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985031.
Sequenz GQNTDIQQIA AKNFTDTSLM YPEDTCKSGP STNTQSGLFN TPPPTPPDLN
Homologie Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 86%, Sheep: 93%
Produktmerkmale This is a rabbit polyclonal antibody against TGIF1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human TGIF1

Target Details TGIF1

Produktdetails anti-TGIF1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-TGIF1 Antikörper (ABIN2784526) Bilder zurück nach oben
Antigen
Andere Bezeichnung TGIF1 (TGIF1 Antibody Abstract)
Hintergrund TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.
Alias Symbols: HPE4, MGC39747, MGC5066, TGIF
Protein Interaction Partner: MDFI, CTBP2, CTBP1, APP, PML, ELAVL1, HDAC1, A2M, AR, SIN3A, SMAD3, LRIF1, MED31, MAPK3, SMAD2, MAPK1, JUN, HMGB1, EEF1A1, FOXH1, SMAD1, SDAD1, STK16, MKKS,
Protein Size: 401
Molekulargewicht 43 kDa
Gen-ID 7050
NCBI Accession NM_170695, NP_733796
UniProt Q15583
Pathways Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation

Anwendungsinformationen

Produktdetails anti-TGIF1 Antikörper Target Details TGIF1 Handhabung Referenzen für anti-TGIF1 Antikörper (ABIN2784526) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 401 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-TGIF1 Antikörper Target Details TGIF1 Anwendungsinformationen Referenzen für anti-TGIF1 Antikörper (ABIN2784526) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TGIF1 Antikörper (ABIN2784526)

Produktdetails anti-TGIF1 Antikörper Target Details TGIF1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Richieri-Costa, Ribeiro: "Variable phenotypic manifestations of a K44N mutation in the TGIF gene." in: Brain & development, Vol. 30, Issue 3, pp. 203-5, 2008

Bilder

Produktdetails anti-TGIF1 Antikörper Target Details TGIF1 Anwendungsinformationen Handhabung Referenzen für anti-TGIF1 Antikörper (ABIN2784526) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-TGFB-Induced Factor Homeobox 1 (TGIF1) (C-Term) antibody (ABIN2784526) WB Suggested Anti-TGIF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: