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TGIF1 Antikörper (AA 208-237)

TGIF1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB14110 unconjugated
Produktnummer ABIN655999
  • Target Alle TGIF1 Antikörper anzeigen
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Bindungsspezifität
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-237
    Reaktivität
    • 48
    • 13
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 41
    • 6
    • 1
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TGIF1 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 27
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    C
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This TGIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF1.
    Klon
    RB14110
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TGIF1 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Andere Bezeichnung
    TGIF1 (TGIF1 Produkte)
    Synonyme
    HPE4 antikoerper, TGIF antikoerper, AA959811 antikoerper, AI462167 antikoerper, Tgif antikoerper, Tfig antikoerper, fa06h05 antikoerper, fb33g11 antikoerper, zgc:55852 antikoerper, wu:fa06h05 antikoerper, wu:fb33g11 antikoerper, hpe4 antikoerper, tgif antikoerper, tgif1 antikoerper, TGFB induced factor homeobox 1 antikoerper, TGFB-induced factor homeobox 1 antikoerper, TGFB induced factor homeobox 1 S homeolog antikoerper, TGIF1 antikoerper, Tgif1 antikoerper, tgif1 antikoerper, tgif1.S antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.
    Molekulargewicht
    43013
    Gen-ID
    7050
    NCBI Accession
    NP_001265611, NP_001265613, NP_001265615, NP_003235, NP_733796, NP_775299, NP_775300, NP_775301, NP_775302, NP_775303, NP_777480
    UniProt
    Q15583
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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