anti-Maus ASXL1 Antikörper für Western Blotting

Recommended ASXL1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Additional Sex Combs Like 1 (Drosophila) (ASXL1) Antikörper
  • asxl1
  • MGC83850
  • mKIAA0978
  • BOPS
  • MDS
  • additional sex combs like 1 (Drosophila)
  • additional sex combs like 1
  • asxl1
  • LOC100341931
  • Asxl1
  • ASXL1
Epitop
AA 521-549
9
8
8
7
3
3
2
1
Reaktivität
Human, Maus
27
24
1
Wirt
Kaninchen
27
9
Klonalität
Polyklonal
Konjugat
Dieser ASXL1 Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
30
21
17
16
16
7
4
3
1
Hersteller
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Bilder

Produktnummer ABIN950543
$ 390.50
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.1474795 ABIN4902962 WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN655084 FACS IF IHC (p) WB Rabbit Ig AA 521-549, Center Anmelden zum Anzeigen Polyclonal 1
1 ABIN207586 ELISA WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1965991 ELISA FACS ICC IF IHC WB Biotin Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN1963315 ELISA FACS ICC IF IHC WB APC Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN1960940 ELISA FACS ICC IF IHC WB Alkaline Phosphatase (AP) Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN1969765 ELISA FACS ICC IF IHC WB FITC Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN1972059 ELISA FACS ICC IF IHC WB HRP Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN2589167 ELISA FACS IF IHC WB Rabbit IgG AA 528-556 Anmelden zum Anzeigen Polyclonal
1 ABIN1974356 ELISA FACS ICC IF IHC WB PE Rabbit IgG AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN5535502 FACS IF IHC (p) WB Rabbit Ig Fraction AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN2205616 FACS IF IHC ELISA WB PE Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205615 IHC ELISA WB HRP Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205611 FACS IF IHC ELISA WB APC Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205613 FACS IF IHC ELISA WB FITC Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205617 FACS IF IHC ELISA WB Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205612 FACS IF IHC ELISA WB Biotin Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN2205610 FACS IF IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 528-556, Center, Internal Region Anmelden zum Anzeigen Polyclonal
1 ABIN1806003 FACS IF IHC (p) WB Rabbit AA 521-549 Anmelden zum Anzeigen Polyclonal
1 ABIN2441632 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Additional Sex Combs Like 1 (Drosophila) (ASXL1) Antikörper
Epitop AA 521-549
(9), (8), (8), (7), (3), (3), (2), (1)
Reaktivität Human, Maus
(27), (24), (1)
Wirt Kaninchen
(27), (9)
Klonalität
Polyklonal
Konjugat Dieser ASXL1 Antikörper ist unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(30), (21), (17), (16), (16), (7), (4), (3), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ASXL1 Antikörper

Target Details ASXL1 Anwendungsinformationen Handhabung Referenzen für anti-ASXL1 Antikörper (ABIN950543) Bilder
Spezifität This antibody detects ASXL1 at Center.
Kreuzreaktivität (Details) Species reactivity (tested):Mouse.
Reinigung Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 521-549 amino acids from the Central region of human ASXL.
Isotyp Ig

Target Details ASXL1

Produktdetails anti-ASXL1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-ASXL1 Antikörper (ABIN950543) Bilder zurück nach oben
Antigen
Andere Bezeichnung ASXL1 (ASXL1 Antibody Abstract)
Hintergrund This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.Synonyms: Additional sex combs-like protein 1, KIAA0978, Putative Polycomb group protein ASXL1
Molekulargewicht 165432 Da
Gen-ID 171023
NCBI Accession NP_056153
Forschungsgebiet Chromatin and Nuclear Signaling
Pathways Retinoic Acid Receptor Signaling Pathway

Anwendungsinformationen

Produktdetails anti-ASXL1 Antikörper Target Details ASXL1 Handhabung Referenzen für anti-ASXL1 Antikörper (ABIN950543) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ASXL1 Antikörper Target Details ASXL1 Anwendungsinformationen Referenzen für anti-ASXL1 Antikörper (ABIN950543) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-ASXL1 Antikörper (ABIN950543)

Produktdetails anti-ASXL1 Antikörper Target Details ASXL1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Abdel-Wahab, Kilpivaara, Patel, Busque, Levine: "The most commonly reported variant in ASXL1 (c.1934dupG;p.Gly646TrpfsX12) is not a somatic alteration." in: Leukemia, Vol. 24, Issue 9, pp. 1656-7, 2010

Szpurka, Jankowska, Makishima, Bodo, Bejanyan, Hsi, Sekeres, Maciejewski: "Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutations." in: Leukemia research, Vol. 34, Issue 8, pp. 969-73, 2010

Sugimoto, Muramatsu, Makishima, Prince, Jankowska, Yoshida, Xu, Nishio, Hama, Yagasaki, Takahashi, Kato, Manabe, Kojima, Maciejewski: "Spectrum of molecular defects in juvenile myelomonocytic leukaemia includes ASXL1 mutations." in: British journal of haematology, Vol. 150, Issue 1, pp. 83-7, 2010

Boultwood, Perry, Zaman, Fernandez-Santamaria, Littlewood, Kusec, Pellagatti, Wang, Clark, Wainscoat: "High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression." in: Leukemia, Vol. 24, Issue 6, pp. 1139-45, 2010

Bilder

Produktdetails anti-ASXL1 Antikörper Target Details ASXL1 Anwendungsinformationen Handhabung Referenzen für anti-ASXL1 Antikörper (ABIN950543) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Additional Sex Combs Like 1 (Drosophila) (ASXL1) (AA 521-549) antibody (ABIN950543) Flow Cytometric analysis of Hela cells (Right Histogram) using ASXL1 antibody (Center...
Immunofluorescence (IF) image for anti-Additional Sex Combs Like 1 (Drosophila) (ASXL1) (AA 521-549) antibody (ABIN950543) Confocal immunofluorescent analysis of ASXL1 Antibody (Center) Cat.-No AP50279PU-N wi...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Additional Sex Combs Like 1 (Drosophila) (ASXL1) (AA 521-549) antibody (ABIN950543) Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis ti...
Western Blotting (WB) image for anti-Additional Sex Combs Like 1 (Drosophila) (ASXL1) (AA 521-549) antibody (ABIN950543) Western blot analysis in mouse liver tissue lysates (35ug/lane) using ASXL1 antibody ...