anti-Human Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa Antikörper für Enzyme Immunoassay

Recommended Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa Antibody

Antigen
Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Antikörper
  • Pol2rb
  • Rpb140
  • Rpb2
  • POL2RB
  • RPB2
  • hRPB140
  • hsRPB2
  • RNA polymerase II subunit B
  • polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
  • DNA-directed RNA polymerase II subunit RPB2
  • polymerase (RNA) II (DNA directed) polypeptide B
  • polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog
  • POLR2B
  • polr2b
  • LOC100640211
  • Polr2b
  • polr2b.L
  • rpb-2
Epitop
AA 796-826, Middle Region
10
8
7
7
4
2
1
1
1
1
Reaktivität
Human
47
19
19
8
7
4
4
4
3
3
3
2
2
Wirt
Kaninchen
47
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
47
21
13
5
4
3
2
Optionen

Bilder

Produktnummer ABIN954239
$ 484.00
Zzgl. Versandkosten $45.00

General

Antigen Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Antikörper
Epitop AA 796-826, Middle Region
(10), (8), (7), (7), (4), (2), (1), (1), (1), (1)
Reaktivität Human
(47), (19), (19), (8), (7), (4), (4), (4), (3), (3), (3), (2), (2)
Wirt Kaninchen
(47)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(2), (2), (2), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(47), (21), (13), (5), (4), (3), (2)
Pubmed 3 Publikationen vorhanden
Hersteller

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Spezifität This antibody recognizes Human POLR2B (Center).
Reinigung Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 796-826 amino acids from the Central region of human POLR2B
Isotyp Ig Fraction

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung POLR2B / RPB2 (POLR2B Antibody Abstract)
Hintergrund This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq].Synonyms: DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit B2, RPB140
Molekulargewicht 133897 Da
Gen-ID 5431
NCBI Accession NP_000929
Pathways Regulatorische RNA Pathways, DNA Reparatur

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lee, Skalnik: "Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 609-18, 2008

Yamaguchi, Mura, Chanarat, Okamoto, Handa: "Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 12, Issue 7, pp. 863-75, 2007

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) (AA 796-826), (Middle Region) antibody (ABIN954239) Western blot analysis of POLR2B Antibody (Center) in 293 cell line lysates (35ug/lane...