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IL-13 Protein

IL13 Spezies: Maus Wirt: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Produktnummer ABIN988037
  • Target Alle IL-13 (IL13) Proteine anzeigen
    IL-13 (IL13) (Interleukin 13 (IL13))
    Biologische Aktivität
    Active
    Spezies
    • 27
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 30
    • 16
    • 8
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP
    Produktmerkmale
    The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.
    Reinheit
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin-Niveau
    Level Less than 1EU/µg of rMuIL-13 as determined by LAL method
    Top Product
    Discover our top product IL13 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    Lagerung
    4 °C
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Andere Bezeichnung
    Interleukin-13 (IL-13) (IL13 Produkte)
    Synonyme
    IL13 Protein, IL-13 Protein, P600 Protein, Il-13 Protein, L13 Protein, interleukin 13 Protein, IL13 Protein, Il13 Protein
    Hintergrund
    IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and mouse IL-13 is cross-species reactive. Synonym:. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, pH 7.4.
    Molekulargewicht
    Approximately 12.3 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.
    Pathways
    JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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