Purified recombinant Human SCF protein Expression System: E.coli Bioactivity: Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED50 for this effect is 20 - 40 ng/mL.
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on Mouse cells, while Mouse and rat SCF are fully active on human cells. Alternative Names: c-Kit Ligand protein, Stem Cell Factor protein, Mast Cell Growth Factor protein, Steel Factor protein, MGF protein