IL1R1 Protein
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- Target Alle IL1R1 Proteine anzeigen
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
- Produktmerkmale
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Purified recombinant Human IL1 R alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to inhibit the IL-1alpha stimulation of Mouse D10S cell. The expected ED50 is 20-40 ng/mL in the presence of 50 pg/mL of IL-1alpha. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product IL1R1 Protein
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Interleukin 1 Receptor, Type I (IL1R1) (AA 20-338) protein (His tag)
IL1R1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type I (IL1R1) (AA 18-332) protein (His tag)IL1R1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor, Type I (IL1R1) protein (Fc Tag)IL1R1 Spezies: Maus Wirt: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Interleukin 1 Receptor, Type I (IL1R1) (AA 19-328) proteinIL1R1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS
Interleukin 1 Receptor, Type I (IL1R1) (AA 18-127) protein (GST tag)IL1R1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (Fc Tag)IL1R1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag,Fc Tag)IL1R1 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag)IL1R1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (Active) protein (His tag)IL1R1 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 1 Receptor, Type I (IL1R1) (AA 357-569) protein (His tag)Crystallography grade IL1R1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in water to a concentration of 0.1 to 1.5 g/mL. Do not vortex.
- Buffer
- Lyophilized from 5 mM Tris, pH 8.0, with 25 mM NaCl.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
- Andere Bezeichnung
- IL1R alpha (IL1R1 Produkte)
- Synonyme
- CD121A Protein, D2S1473 Protein, IL-1R-alpha Protein, IL1R Protein, IL1RA Protein, P80 Protein, CD121a Protein, CD121b Protein, IL-iR Protein, Il1r-1 Protein, DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, interleukin 1 receptor type 1 Protein, interleukin 1 receptor, type I Protein, interleukin 1 receptor-like 1 Protein, IL1R1 Protein, Il1r1 Protein, Il1rl1 Protein
- Hintergrund
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Interleukin-1 receptor antagonist (IL1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease.
Alternative Names: IL 1 protein, IL 1, ICIL-1RA protein, Interleukin 1R alpha protein, IL-1R alpha protein, IL1, IL-1RN protein, IRAP protein, IL-1, IL-1 protein, IL-1Ra protein - Molekulargewicht
- 17.2 kDa
- Pathways
- NF-kappaB Signalweg, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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