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FGF19 Protein

FGF19 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure Active
Produktnummer ABIN935365
  • Target Alle FGF19 Proteine anzeigen
    FGF19 (Fibroblast Growth Factor 19 (FGF19))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    Human
    Quelle
    • 9
    • 4
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
    Produktmerkmale
    Purified recombinant Human FGF19 protein
    Expression System: E.coli
    Bioactivity: Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/mL.
    Reinheit
    > 95 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product FGF19 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 5 mM Tris, pH 7.6, with 75 mM NaCl.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Borello, Cobos, Long, McWhirter, Murre, Rubenstein: "FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development." in: Neural development, Vol. 3, pp. 17, (2008) (PubMed).

  • Target
    FGF19 (Fibroblast Growth Factor 19 (FGF19))
    Andere Bezeichnung
    FGF19 (FGF19 Produkte)
    Synonyme
    FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein
    Hintergrund
    The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF19 is expressed during the brain development and embryogenesis.
    Alternative Names: FGF 19 protein, FGF19, FGFJ protein, FGF-19, FGF 19, Fibroblast Growth Factor-19 protein, FGF-19 protein, FGF-19 protein
    Molekulargewicht
    21.8 kDa
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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