IL-11 Protein
-
- Target Alle IL-11 (IL11) Proteine anzeigen
- IL-11 (IL11) (Interleukin 11 (IL11))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Sequenz
- MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
- Produktmerkmale
-
Purified recombinant Human IL11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg) of IL-11.
- Top Product
- Discover our top product IL11 Protein
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute in 3 mM Tris, pH 8.0 at the stock concentration of 3 g/mL.
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- Target
- IL-11 (IL11) (Interleukin 11 (IL11))
- Andere Bezeichnung
- IL11 (IL11 Produkte)
- Synonyme
- IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
- Hintergrund
-
IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Alternative Names: AGIF protein, IL-11 protein, IL-11, IL11, IL-11 protein, Interleukin 11 protein, Adipogenesis inhibitory factor protein, IL 11, IL 11 protein - Molekulargewicht
- 19.1 kDa
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
-