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IL-11 Protein

IL11 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN934619
  • Target Alle IL-11 (IL11) Proteine anzeigen
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 20
    • 10
    • 2
    • 2
    Human
    Quelle
    • 13
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
    Produktmerkmale
    Purified recombinant Human IL11 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per µg (1 EU/µg) of IL-11.
    Top Product
    Discover our top product IL11 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 3 mM Tris, pH 8.0 at the stock concentration of 3 g/mL.
    Buffer
    Supplied as a lyophilized powder.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Andere Bezeichnung
    IL11 (IL11 Produkte)
    Synonyme
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Hintergrund
    IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
    Alternative Names: AGIF protein, IL-11 protein, IL-11, IL11, IL-11 protein, Interleukin 11 protein, Adipogenesis inhibitory factor protein, IL 11, IL 11 protein
    Molekulargewicht
    19.1 kDa
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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