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IL-31 Protein (His tag)

IL31 Spezies: Human Wirt: HEK-293 Cells Recombinant
Produktnummer ABIN7536345
  • Target Alle IL-31 (IL31) Proteine anzeigen
    IL-31 (IL31) (Interleukin 31 (IL31))
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 5
    • 4
    • 2
    • 1
    Human
    Quelle
    • 12
    • 6
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL-31 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human IL-31 Protein
    Sequenz
    SHTLPVRLLR PSDDVQKIVE ELQSLSKMLL KDVEEEKGVL VSQNYTLPCL SPDAQPPNNI HSPAIRAYLK TIRQLDNKSV IDEIIEHLDK LIFQDAPETN ISVPTDTHEC KRFILTISQQ FSECMDLALK SLTSGAQQAT T
    Spezifität
    Ser24-Thr164
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    < 0.1EU/μg
    Top Product
    Discover our top product IL31 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Konzentration
    0.84 mg/mL
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Andere Bezeichnung
    IL-31 (IL31 Produkte)
    Synonyme
    IL-31 Protein, 1700013B14Rik Protein, IL31 Protein, interleukin 31 Protein, IL31 Protein, Il31 Protein
    Hintergrund

    Description: IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

    Name: IL-31,IL31

    Gen-ID
    386653
    UniProt
    Q6EBC2
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