FGFRL1 Protein (His tag)

Produktnummer ABIN7520015

Produktdetails

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses FGFRL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FGFR-5/FGFRL1 Protein

Sequenz: ARGPPKMADK VVPRQVARLG RTVRLQCPVE GDPPPLTMWT KDGRTIHSGW SRFRVLPQGL KVKQVEREDA GVYVCKATNG FGSLSVNYTL VVLDDISPGK ESLGPDSSSG GQEDPASQQW ARPRFTQPSK MRRRVIARPV GSSVRLKCVA SGHPRPDITW MKDDQALTRP EAAEPRKKKW TLSLKNLRPE DSGKYTCRVS NRAGAINATY KVDVIQRTRS KPVLTGTHPV NTTVDFGGTT SFQCKVRSDV KPVIQWLKRV EYGAEGRHNS TIDVGGQKFV VLPTGDVWSR PDGSYLNKLL ITRARQDDAG MYICLGANTM GYSFRSAFLT VLPDPKPPGP PVASSSSATS LPWP

Spezifität: Ala25-Pro378

Reinheit: > 92 % by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: < 0.1 EU/μg of the protein by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Antigendetails

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Andere Bezeichnung: FGFR-5/FGFRL1 (FGFRL1 Produkte)

Synonyme: fgfrl1 Protein, zgc:64084 Protein, FGFR5 Protein, FGFR5beta Protein, FGFR5gamma Protein, Fgfr5 Protein, FHFR Protein, XFGFRL1 Protein, Xndk Protein, fgfrl1-a Protein, fgfrl1-b Protein, ndk Protein, im:7154242 Protein, fibroblast growth factor receptor like 1a Protein, fibroblast growth factor receptor-like 1 Protein, fibroblast growth factor receptor like 1 Protein, fibroblast growth factor receptor like 1 L homeolog Protein, fibroblast growth factor receptor like 1b Protein, fgfrl1a Protein, Fgfrl1 Protein, FGFRL1 Protein, fgfrl1.L Protein, fgfrl1b Protein

Hintergrund:

Description: Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A unique feature of FGFRL1/FGFR5 is that it does not contain an intracellular tyrosine kinase domain. Some muscle types, including the muscles of the tongue and the diaphragm, express FGFRL1/FGFR5 at relatively high level.

Name: FGF homologous factor receptor,FGF R5,FGF receptor-like protein 1,FGFR5,FGFR-5,FGFRL1,FGFR-like protein,FHFR,Fibroblast growth factor receptor 5,fibroblast growth factor receptor-like 1,FGFRL1

Gen-ID: 53834

UniProt: Q8N441

Pathways: RTK Signalweg