FGFRL1 Protein (His tag)

Produktnummer ABIN7318471

Produktdetails

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses FGFRL1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human FGFR5/FGFRL1 Protein (His Tag)(Active)

Sequenz: Ala25-Pro378

Produktmerkmale: Recombinant Human Fibroblast Growth Factor Receptor-Like 1 is produced by our Mammalian expression system and the target gene encoding Ala25-Pro378 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human FGFb(Cat: PKSH032437) at 2μg/ml(100 μl/well) can bind Human FGFRL1-His. The ED50 of Human FGFRL1-His is 0.0345 ug/ml.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Andere Bezeichnung: FGFR5/FGFRL1 (FGFRL1 Produkte)

Synonyme: fgfrl1 Protein, zgc:64084 Protein, FGFR5 Protein, FGFR5beta Protein, FGFR5gamma Protein, Fgfr5 Protein, FHFR Protein, XFGFRL1 Protein, Xndk Protein, fgfrl1-a Protein, fgfrl1-b Protein, ndk Protein, im:7154242 Protein, fibroblast growth factor receptor like 1a Protein, fibroblast growth factor receptor-like 1 Protein, fibroblast growth factor receptor like 1 Protein, fibroblast growth factor receptor like 1 L homeolog Protein, fibroblast growth factor receptor like 1b Protein, fgfrl1a Protein, Fgfrl1 Protein, FGFRL1 Protein, fgfrl1.L Protein, fgfrl1b Protein

Hintergrund:

Background: Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.

Synonym: Fibroblast Growth Factor Receptor-Like 1, FGF Receptor-Like Protein 1, FGF Homologous Factor Receptor, FGFR-Like Protein, Fibroblast Growth Factor Receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR

Molekulargewicht: 39.9 kDa

UniProt: Q8N441

Pathways: RTK Signalweg