BRCA1 Protein (AA 1564-1863) (His tag)

Produktnummer ABIN7505164

Produktdetails

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1564-1863

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses BRCA1 Protein ist gelabelt mit His tag.

Sequenz: Leu 1564-Tyr 1863

Produktmerkmale: A DNA sequence encoding the Human BRCA1 protein (P38398) (Leu 1564-Tyr 1863) was expressed with a N-His.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Andere Bezeichnung: BRCA1 (BRCA1 Produkte)

Synonyme: BRCAI Protein, BRCC1 Protein, BROVCA1 Protein, IRIS Protein, PNCA4 Protein, PPP1R53 Protein, PSCP Protein, RNF53 Protein, iris Protein, pscp Protein, brcai Protein, brcc1 Protein, rnf53 Protein, brca1 Protein, BRCA1 Protein, LOC100224649 Protein, BRCA1, DNA repair associated Protein, breast cancer 1 Protein, breast cancer 1, early onset Protein, breast cancer 1 L homeolog Protein, BRCA1 Protein, brca1 Protein, LOC755086 Protein, Brca1 Protein, brca1.L Protein

Hintergrund:

Background: RCA1,also named as RNF53,plays a central role in DNA repair by facilitating cellular response to DNA repair. It is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. The BRCA1-BAR

Synonym: BRCA 1,BRCA1,BRCA1 DNA repair associated,BRCA1/BRCA2 containing complex subunit 1,BRCA1/BRCA2-containing complex,subunit 1,BRCA1,BRCAI,BRCC 1,BRCC1,Breast and ovarian cancer susceptibility protein 1,Breast Cancer 1,Breast Cancer 1 Early Onset,Breast cance

Molekulargewicht: 32.89 kDa

UniProt: P38398

Pathways: Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus