TNFSF15 Protein (AA 72-251) (Fc Tag)

Produktnummer ABIN7504549

Produktdetails

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Protein-Typ: Recombinant

Proteineigenschaft: AA 72-251

Spezies: Cynomolgus, Rhesusaffen

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFSF15 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Cynomolgus/Rhesus macaque TNFSF15 Protein

Sequenz: Leu72-Leu251

Produktmerkmale: Recombinant Cynomolgus/Rhesus macaque TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Leu72-Leu251.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))

Andere Bezeichnung: TNFSF15 (TNFSF15 Produkte)

Synonyme: TTPAL Protein, TL1 Protein, TL1A Protein, VEGI Protein, VEGI192A Protein, Tl1 Protein, Tl1a Protein, Vegi Protein, tumor necrosis factor superfamily member 15 Protein, TNF superfamily member 15 Protein, tumor necrosis factor (ligand) superfamily, member 15 Protein, TNFSF15 Protein, Tnfsf15 Protein

Hintergrund: TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.

Molekulargewicht: 44.82 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5UA22

Pathways: Positive Regulation of Endopeptidase Activity, Autophagie