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DLL4 Protein (AA 27-524) (His tag)

DLL4 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Produktnummer ABIN7504312
  • Target Alle DLL4 Proteine anzeigen
    DLL4 (delta-Like 4 (DLL4))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 27-524
    Spezies
    • 12
    • 5
    • 3
    Human
    Quelle
    • 8
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses DLL4 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Human DLL4 Protein
    Sequenz
    Ser27-Pro524
    Produktmerkmale
    Recombinant Human DLL4 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser27-Pro524.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product DLL4 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DLL4 (delta-Like 4 (DLL4))
    Andere Bezeichnung
    DLL4 (DLL4 Produkte)
    Synonyme
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    Hintergrund
    Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
    Molekulargewicht
    55.38 kDa. Due to glycosylation, the protein migrates to 56-70 kDa based on Tris-Bis PAGE result.
    Pathways
    Notch Signalweg
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