IFNAR1 Protein (mFc Tag)

Produktnummer ABIN7490868

Produktdetails

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IFNAR1 Protein ist gelabelt mit mFc Tag.

Verwendungszweck: Recombinant human IFNAR1 Protein with C-terminal Mouse Fc tag

Spezifität: IFNAR1 (Lys28-Lys436) mFc (Pro99-Lys330)

Produktmerkmale: Extracellular Domain Protein

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung: IFNAR1 (IFNAR1 Produkte)

Synonyme: ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein

Hintergrund: Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,CRF2-1,Type I interferon receptor 1
Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]

Molekulargewicht: predicted molecular mass of 73 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR1-mFc is 100-130 kDa due to glycosylation.

UniProt: P17181

Pathways: JAK-STAT Signalweg, Hepatitis C