ApoE3 Protein (AA 19-317) (Fc Tag)
ApoE3
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE
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- Target Alle ApoE3 Produkte
- ApoE3 (Apolipoprotein E3 (ApoE3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 19-317
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ApoE3 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human APOE3/Apolipoprotein E Protein
- Sequenz
- Lys19-His317
- Produktmerkmale
- Recombinant Human APOE3/Apolipoprotein E Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Lys19-His317.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.41 μM as determined in SPR assay (Biacore T200). See testing image for detail.
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Apolipoprotein E3 (ApoE3) (AA 19-317) protein (His tag)
ApoE3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Apolipoprotein E3 (ApoE3) (AA 19-317) protein (His tag,Biotin)ApoE3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ApoE3 (Apolipoprotein E3 (ApoE3))
- Andere Bezeichnung
- APOE3 (ApoE3 Produkte)
- Synonyme
- AD2 Protein, LDLCQ5 Protein, LPG Protein, apolipoprotein E Protein, APOE Protein
- Hintergrund
- Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
- Molekulargewicht
- 59.76 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- UniProt
- P02649
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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