SARS-CoV-2 Spike S2 Protein (BA.2 - Omicron) (Biotin,His-Avi Tag)

Produktnummer ABIN7447847

Produktdetails

Target: SARS-CoV-2 Spike S2

Protein-Typ: Recombinant

Proteineigenschaft: BA.2 - Omicron

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike S2 Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.2/Omicron)

Sequenz: Ser 686 - Pro 1213

Produktmerkmale: Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.2/Omicron) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1 (N764K, D796Y, Q954H, N969K, F817P, A892P, A899P, A942P, K986P, V987P). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2/3/4/5). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.

Reinheit: 95,00 %

Endotoxin-Niveau: 1.0 EU per μg

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.7 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: SARS-CoV-2 Spike S2

Andere Bezeichnung: SARS-CoV-2 Spike S2 protein (SARS-CoV-2 Spike S2 Produkte)

Synonyme: E2 Protein, Surface Glycoprotein Protein, S Protein

Substanzklasse: Viral Protein

Hintergrund: Synonyms:Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molekulargewicht: 61.7 kDa